Patient-based assessment in dyspepsia - Development and validation of Dyspepsia Symptom Severity Index (DSSI)
Patient-based assessment in dyspepsia - Development and validation of Dyspepsia Symptom Severity Index (DSSI)
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DOI：
10.1023/a:1005558204440
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发表时间：
2000-06-01
影响因子：
3.1
通讯作者：
Koch, KL
中科院分区：
文献类型：
--
作者：
Leidy, NK;Farup, C;Koch, KL
本文描述了一种新的自我报告量表的开发和测试。消化不良症状严重程度指数（DSSI），用于评估消化不良通常相关症状的严重程度。该工具基于文献、焦点小组和胃肠病学家的反馈；48名患者和24名对照者参加了测试。患者完成DSSI和症状日记来测试并发效度；在21例稳定的患者中评估一周的重复性。DSSI共有20个条目，分为三个分量表，分别代表反流、溃疡和运动障碍样症状。亚量表内部一致性水平（alpha）高（0.84-0.89），总分alpha水平非常好（0.76,0.80），评分可重复（ICC = 0.90-0.92）。DSSI与日记的相关性为中~强（r = 0.33 ~ 0.77; P < 0.05）。患者报告的症状明显比对照组严重（P < 0.001）。结果表明DSSI是评估功能性消化不良患者症状严重程度的可靠和有效的工具。
This paper describes the development and testing of a new self-report measure. the Dyspepsia Symptom Severity Index (DSSI), for assessing the severity of symptoms commonly associated with dyspepsia. The instrument was based on the literature, focus groups, and feedback from gastroenterologists; 48 patients and 24 controls participated in testing. Patients completed the DSSI and a symptom diary to test concurrent validity; one-week reproducibility was evaluated in 21 stable patients. Three subscales comprise the 20-item DSSI, representing reflux-, ulcer-, and dysmotility-like symptoms. Subscale internal consistency levels (alpha) were high (0.84-0.89), total score alpha levels were very good (0.76, 0.80), and scores were reproducible (ICC = 0.90-0.92). Correlations between the DSSI and diary were moderate to strong (r = 0.33-0.77; P < 0.05). Patients reported significantly more severe symptoms than controls (P < 0.001). Results indicate the DSSI is a reliable and valid tool for evaluating symptom severity in patients with functional dyspepsia.