Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture
Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture
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DOI：
10.1155/2014/161952
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发表时间：
2014-01-01
影响因子：
0.7
通讯作者：
Halepota, Maqbool
中科院分区：
文献类型：
--
作者：
Ahmed, Zartaj;Ramanathan, Ramesh K.;Halepota, Maqbool
原发性中枢神经系统淋巴瘤（PCNSL）是一种罕见的局限于中枢神经系统的非霍奇金淋巴瘤。局部复发是常见的，但颅外或皮下转移是罕见的，只有少数病例在文献中报道。我们报告一位63岁的男性病人，对PCNSL的治疗反应良好，但在两年半后复发，在以前的腰椎穿刺部位出现腰骶结节，原因是显微镜下肿瘤种植。治疗PCNSL患者的临床医生必须对颅外孤立性复发的可能性保持警惕，即使在初始疾病消退后也是如此，因为及时治疗可以获得良好的结果。
Primary CNS lymphoma (PCNSL) is a rare non-Hodgkin's lymphoma confined to the CNS. Local relapse of this disease is common, but extracranial or subcutaneous metastasis is rare with only a few cases being reported in literature. We report a 63-year-old male patient, who responded well to treatment for PCNSL but relapsed two and half years later with a lumbosacral nodule at the site of a previous lumbar puncture due to microscopic tumor seeding. Clinicians treating patients with PCNSL must remain alert to the possibility of extracranial solitary relapse even after the resolution of initial disease because prompt treatment can result in a good outcome.