Relationship between bone tissue strain and lattice strain of HAp crystals in bovine cortical bone under tensile loading
Relationship between bone tissue strain and lattice strain of HAp crystals in bovine cortical bone under tensile loading
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DOI：
10.1016/j.jbiomech.2006.07.003
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发表时间：
2007-01-01
影响因子：
2.4
通讯作者：
Tadano, Shigeru
中科院分区：
文献类型：
--
作者：
Fujisaki, Kazuhiro;Tadano, Shigeru
皮质骨是由羟基磷灰石（HAp）和胶原组成的复合材料。由于HAp是晶体结构，因此X射线衍射方法可用于测量HAp晶体的应变。然而，已知骨组织中的HAp晶体具有低结晶度。作者提出了一种X射线衍射方法来测量HAp晶体的晶格应变的扩散强度分布，由于低结晶度。该方法大大提高了应变测量的精度。为了确认通过测量HAp晶体的应变来估计骨组织应变的可能性，本工作研究了宏观尺度上的骨组织应变与微观尺度上的HAp晶体的晶格应变之间的关系。在拉伸载荷下进行X射线衍射实验。从牛股骨干的皮质区域切割40 x 6 x 0.8 mm大小的条状骨样本。在样品的纵向方向上施加逐步拉伸载荷。通过检测透射穿过试样的衍射X射线束，直接测量加载方向上的晶格应变。结果，HAp晶体的晶格应变显示出比通过应变计测量的骨组织应变低的值。用HAp晶体的平均晶格应变和弹性模量描述骨组织应变。(C)2006爱思唯尔有限公司保留所有权利。
Cortical bone is a composite material composed of hydroxyapatite (HAp) and collagen. As HAp is a crystalline structure, an X-ray diffraction method is available to measure the strain of HAp crystals. However, HAp crystals in bone tissue have been known to have the low degree of crystallization. Authors have proposed an X-ray diffraction method to measure the lattice strain of HAp crystals from the diffusive intensity profile due to low crystallinity. The precision of strain measurement was greatly improved by this method. In order to confirm the possibility of estimating the bone tissue strain with measurements of the strain of HAp crystals, this work investigates the relationship between bone tissue strain on a macroscopic scale and the lattice strain of HAp crystals on a microscopic scale. The X-ray diffraction experiments were performed under tensile loading. Strip bone specimens of 40 x 6 x 0.8 mm in size were cut from the cortical region of a shaft of bovine femur. A stepwise tensile load was applied in the longitudinal direction of the specimen. By detecting the diffracted X-ray beam transmitted through the specimen, the lattice strain was directly measured in the loading direction. As a result, the lattice strain of HAp crystals showed lower value than the bone tissue strain measured by a strain gage. The bone tissue strain was described with the mean lattice strain of the HAp crystals and the elastic modulus. (C) 2006 Elsevier Ltd. All rights reserved.