Alcohol use disorders and associated factors among people living with HIV who are attending services in south west Ethiopia.
Alcohol use disorders and associated factors among people living with HIV who are attending services in south west Ethiopia.
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DOI：
10.1186/1756-0500-7-828
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发表时间：
2014-11-24
影响因子：
1.8
通讯作者：
Hanlon C
中科院分区：
文献类型：
--
作者：
Soboka M;Tesfaye M;Feyissa GT;Hanlon C
在高收入国家，人类免疫缺陷病毒（PLHIV）感染者的酒精使用障碍（AUD）与抗逆转录病毒药物依从性差和艾滋病毒相关结局恶化有关。在撒哈拉以南非洲接受艾滋病毒服务的人中，对AUD知之甚少。对2012年9月在吉玛大学专科医院接受艾滋病毒服务的艾滋病毒感染者进行了横断面研究。世界卫生组织的酒精使用障碍识别工具（AUDIT）被用来衡量可能的危险，有害和依赖性使用酒精（酒精使用障碍）。AUDs和其他变量之间的关联进行了探讨，使用逻辑回归分析。p值<0.25的与AUD相关的所有变量均纳入最终多变量模型中。AUDs的总患病率为32.6%，其中危险使用、有害使用和酒精依赖分别占总患病率的24.7%、2.8%和5.1%。接受抗逆转录病毒治疗的患者与未接受过抗逆转录病毒治疗的患者相比，AUD的患病率无显著差异（32.6% vs. 38.6%）。在26.0%和44.1%的女性和男性中分别确定了AUDs。男性、吸烟和心理困扰与AUDs独立呈正相关。在我们对埃塞俄比亚艾滋病毒感染者进行的基于设施的调查中发现的AUDs的高患病率突出表明，需要将AUDs的有效和可行干预措施纳入艾滋病毒护理。
Alcohol use disorders (AUDs) in persons living with human immunodeficiency virus (PLHIV) in high-income countries have been associated with poor adherence to antiretroviral medications and worse HIV-related outcomes. Little is known about AUDs among people attending HIV services in sub-Saharan Africa. Across-sectional study was carried out among PLHIV who attended HIV services at Jimma University Specialized Hospital in September 2012. The World Health Organization’s Alcohol Use Disorders Identification Tool (AUDIT) was used to measure probable hazardous, harmful and dependent use of alcohol (‘alcohol use disorders’). Associations between AUDs and other variables were explored using logistic regression analysis. All variables associated with AUDs with a p value <0.25 were included in the final multivariable model. The overall prevalence of AUDs was 32.6%, with hazardous use, harmful use and alcohol dependence accounting for 24.7%, 2.8% and 5.1% of the total, respectively. There was no significant difference in the prevalence of AUDs in persons receiving antiretroviral treatment compared to those who were antiretroviral therapy naïve (32.6% vs. 38.6%). AUDs were identified in 26.0% and 44.1% of females and males, respectively. Male gender, smoking cigarettes and psychological distress were positively associated independently with AUDs. The high prevalence of AUDs detected in our facility-based survey of PLHIV in Ethiopia highlights the need to integrate delivery of effective and feasible interventions for AUDs into HIV care.