Endoscopic Findings of Enteropathy-Associated T-Cell Lymphoma Type II: A Case Series.
Endoscopic Findings of Enteropathy-Associated T-Cell Lymphoma Type II: A Case Series.
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DOI：
10.5009/gnl14457
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发表时间：
2016-01
期刊：
影响因子：
3.4
通讯作者：
Kim JJ
中科院分区：
文献类型：
--
作者：
Hong YS;Woo YS;Park G;Lee K;Kang SH;Lee HW;Kim ER;Hong SN;Chang DK;Kim YH;Rhee PL;Kim JJ
肠病相关性T细胞淋巴瘤（EATL）是一种罕见的起源于肠道的淋巴结T细胞淋巴瘤。已经报道了两种类型的EATL。与经典的EATL I型相反，EATL II型零星发生，与乳糜泻无关，占所有EATL病例的10%至20%。2009年1月至2012年9月，我们诊所共诊断出5例EATL II型病例。5例患者中有4例是在内窥镜检查的帮助下确诊的。在这4名患者中，其中2名患者同时累及小肠和大肠，而在另外2名患者中，EATL仅限于小肠。常见的内镜检查结果包括无数细小颗粒（也称为马赛克粘膜模式）和小肠病变中粘膜弥漫性增厚伴半圆形浅溃疡。相反，结肠内镜检查结果是非特异性的，不能区分EATL II型与其他疾病。关于EATL的代表性内窥镜检查结果，只有少数已发表的报告。在这里，我们提出的临床和内镜检查结果的四例EATL II型内镜诊断。
Enteropathy-associated T-cell lymphoma (EATL) is a rare extranodal T-cell lymphoma arising from the intestine. Two types of EATL have been reported. In contrast to the classic EATL type I, EATL type II occurs sporadically, is unrelated to celiac disease, and comprises 10% to 20 % of all EATL cases. A total of five cases of EATL type II were diagnosed at our clinic from January 2009 to September 2012. Four of the five patients were diagnosed with the help of endoscopy. Among the four patients, two of the cases involved both the small and large intestines, whereas in the other two patients, EATL was limited to the small intestine. Common endoscopic findings included innumerable fine granularities (also called mosaic mucosal patterns) and diffuse thickening of the mucosa with a semicircular shallow ulceration in the lesions of the small bowel. In contrast, the endoscopic findings of the colon were nonspecific and could not distinguish EATL type II from other diseases. There are only few published reports regarding the representative endoscopic findings of EATL. Here, we present the clinical and endoscopic findings of four cases of EATL type II diagnosed by endoscopy.