Which Risk Model to Use? Clinical Implications of the ACS MRI Screening Guidelines
Which Risk Model to Use? Clinical Implications of the ACS MRI Screening Guidelines
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DOI：
10.1158/1055-9965.epi-12-0570
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发表时间：
2013-01-01
影响因子：
3.8
通讯作者：
Hughes, Kevin S.
中科院分区：
文献类型：
--
作者：
Ozanne, Elissa M.;Drohan, Brian;Hughes, Kevin S.
美国癌症协会（ACS）指南定义了适当使用MRI作为乳腺癌筛查的乳房X线摄影的辅助手段。建议使用三种风险评估模型来确定女性是否有足够的风险来保证使用这种昂贵的筛查工具，然而，这些模型的实际应用尚未得到探索。我们试图了解这些模型在社区环境中接受乳房X光检查的女性的行为。我们对5，894名在社区医院接受乳房X线摄影筛查的妇女进行了回顾性分析，并根据ACS指南评估了她们接受MRI的资格。在5，894名女性中，342名（5.8%）符合MRI条件，但我们发现每个模型确定的合格女性人数存在显着差异。我们的研究结果表明，这些模型识别非常不同的人群，这意味着ACS指南值得进一步发展和考虑。癌症流行病学生物标志物Prev; 22（1）; 146-9。(C)2012年AACR。
The American Cancer Society (ACS) guidelines define the appropriate use of MRI as an adjunct to mammography for breast cancer screening. Three risk assessment models are recommended to determine if women are at sufficient risk to warrant the use of this expensive screening tool, however, the real-world application of these models has not been explored. We sought to understand how these models behave in a community setting for women undergoing mammography screening. We conducted a retrospective analysis of 5,894 women, who received mammography screening at a community hospital and assessed their eligibility for MRI according to the ACS guidelines. Of the 5,894 women, 342 (5.8%) were eligible for MRI, but we found significant differences in the number of eligible women identified by each model. Our results indicate that these models identify very different populations, implying that the ACS guidelines deserve further development and consideration. Cancer Epidemiol Biomarkers Prev; 22(1); 146-9. (C) 2012 AACR.