Multimicroelectrode stimulation within the cat L6 spinal cord: influences of electrode combinations and stimulus interleave time on knee joint extension torque.
Multimicroelectrode stimulation within the cat L6 spinal cord: influences of electrode combinations and stimulus interleave time on knee joint extension torque.
复制标题
猫 L6 脊髓内的多微电极刺激：电极组合和刺激交错时间对膝关节伸展扭矩的影响。
DOI：
10.1109/86.830943
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Roppolo,JR
中科院分区：
文献类型：
--
作者：
Tai,C;Booth,AM;Robinson,CJ;deGroat,WC;Roppolo,JR
在猫L6脊髓内的多微电极刺激期间，激活的电极的数量、它们的间隔距离和刺激交错时间都影响等长膝关节伸展扭矩。与单电极或双电极刺激相比，三电极组合刺激引起的扭矩可以增强或抑制。当比较双电极组合与单电极刺激时，注意到类似的差异。通过交错两个或三个微电极的刺激，相对疲劳没有显着改善。与非交错刺激引起的伸展扭矩反应相比，当电极距离为2.0 mm或更小时，两个微电极组合交错刺激引起的扭矩降低，当电极距离为3.0 mm时，扭矩增加。如果要在这些电极之间产生抑制效应，则设计多微电极脊髓刺激的最佳刺激策略将具有挑战性和复杂性。避免了为了减少肌肉疲劳，可能需要异步的交错刺激策略。
During multimicroelectrode stimulation within the cat L6 spinal cord, the number of electrodes activated, their separation distance, and the stimulus interleave time all influenced isometric knee joint extension torque. The torque evoked by stimulation with a three electrode combination could be enhanced or suppressed when compared with that evoked by single or paired electrode stimulation. A similar difference was noted when comparing two electrode combination versus single electrode stimulation. Relative fatigue was not improved significantly by interleaving the stimuli from two or three microelectrodes. Compared with the extension torque response evoked by noninterleaved stimulation, torque evoked by interleaved stimulation with the two microelectrode combination was decreased when the electrode distance was 2.0 mm or less and increased when the electrode distance was 3.0 mm. Designing an optimal stimulation strategy for multimicroelectrode spinal cord stimulation will be challenging and complex if a suppression effect among these electrodes is to be avoided. To reduce muscle fatigue, an asynchronous, interleaved strategy of stimulation may be required.