Plant peroxisomes: recent discoveries in functional complexity, organelle homeostasis, and morphological dynamics.

Plant peroxisomes: recent discoveries in functional complexity, organelle homeostasis, and morphological dynamics.
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DOI:
10.1016/j.pbi.2016.07.008
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发表时间:
2016-12
影响因子:
9.5
通讯作者:
Bartel B
Bartel B
中科院分区:
生物学2区
文献类型:
--
作者:
Reumann S;Bartel B

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过氧化物酶体是植物生命所必需的。这些细胞器容纳产生和释放活性氧的各种代谢过程。我们的知识的途径和机制,依赖于过氧化物酶体及其组成酶继续增长,在这篇评论中,我们强调最近的进展,了解过氧化物酶体酶和代谢过程的身份和生物学功能。我们还回顾了过氧化物酶体基质和膜蛋白如何从它们的合成位点进入细胞器。过氧化物酶体的稳态是由特定的降解机制,我们讨论了专门的自噬和过氧化物酶体蛋白酶的贡献,整个过氧化物酶体和过氧化物酶体酶的损坏或多余的降解。最后,我们回顾了过氧化物酶体如何灵活地改变它们的形态,以促进细胞器间的接触。
Peroxisomes are essential for life in plants. These organelles house a variety of metabolic processes that generate and inactivate reactive oxygen species. Our knowledge of pathways and mechanisms that depend on peroxisomes and their constituent enzymes continues to grow, and in this review we highlight recent advances in understanding the identity and biological functions of peroxisomal enzymes and metabolic processes. We also review how peroxisomal matrix and membrane proteins enter the organelle from their sites of synthesis. Peroxisome homeostasis is regulated by specific degradation mechanisms, and we discuss the contributions of specialized autophagy and a peroxisomal protease to the degradation of entire peroxisomes and peroxisomal enzymes that are damaged or superfluous. Finally, we review how peroxisomes can flexibly change their morphology to facilitate inter-organellar contacts.
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