The advantage of early treatment intervention in recurrent depression.
The advantage of early treatment intervention in recurrent depression.
复制标题
早期治疗干预复发性抑郁症的优势。
DOI：
10.1001/archpsyc.1989.01810090013002
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发表时间：
1989
影响因子：
--
通讯作者：
Perel,JM
中科院分区：
文献类型：
--
作者：
Kupfer,DJ;Frank,E;Perel,JM
关于抑郁症治疗的两个关键问题仍未得到解答：早期治疗干预是否会缩短发作时间，以及先前成功的治疗是否会在随后的发作期间产生更快的反应。一组 45 名复发性重度抑郁症患者以类似的方式连续两次接受药物治疗和心理治疗相结合，显示稳定的平均时间在 11 至 12 周之间。然而，第二次治疗发作时的早期干预显着缩短了抑郁发作的总时间约 4 至 5 个月。
Two key questions regarding the treatment of depression remain unanswered: whether early treatment intervention will shorten the length of the episode and whether a previously successful treatment will be associated with a more rapid response when administered during the subsequent episode. A group of 45 patients with recurrent major depression treated with combined pharmacotherapy and psychotherapy in a similar fashion for two consecutive episodes showed comparable mean times to stabilization of between 11 and 12 weeks. However, the early intervention in the second treatment episode significantly shortened the overall length of the depressive episode by approximately 4 to 5 months.