Detection of Paroxysms in Long-Term, Single-Channel EEG-Monitoring of Patients with Typical Absence Seizures.
Detection of Paroxysms in Long-Term, Single-Channel EEG-Monitoring of Patients with Typical Absence Seizures.
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DOI：
10.1109/jtehm.2017.2649491
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发表时间：
2017
影响因子：
3.4
通讯作者：
Duun-Henriksen J
中科院分区：
文献类型：
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作者：
Kjaer TW;Sorensen HBD;Groenborg S;Pedersen CR;Duun-Henriksen J
失神发作与脑电(EEG)中2.5-5赫兹的全身棘波放电有关。患者、父母或医生很少意识到癫痫发作的持续时间或发生率。6名患者使用便携式EEG设备进行了四次24小时的监测，以评估门诊患者被监测的容易程度，以及自动癫痫检测算法识别缺席的情况。基于特定于患者的建模，我们实现了98.4%的灵敏度，每小时仅有0.23次错误检测。这产生了临床满意的性能，阳性预测值为87.1%。便携式脑电记录仪识别癫痫门诊患者的发作事件，对于处理失神癫痫的患者和医生来说是一种很有前途的工具。尽管EEG设备的尺寸很小，但一些儿童仍然抱怨该设备的侵犯性。我们的目标是开发不那么显眼但仍然非常有效的设备，例如隐藏在耳道或皮肤下的设备。用于对失神发作儿童进行非常长期记录的动态脑电记录装置。
Absence seizures are associated with generalized 2.5–5 Hz spike-wave discharges in the electroencephalogram (EEG). Rarely are patients, parents, or physicians aware of the duration or incidence of seizures. Six patients were monitored with a portable EEG-device over four times 24 h to evaluate how easily outpatients are monitored and how well an automatic seizure detection algorithm can identify the absences. Based on patient-specific modeling, we achieved a sensitivity of 98.4% with only 0.23 false detections per hour. This yields a clinically satisfying performance with a positive predictive value of 87.1%. Portable EEG-recorders identifying paroxystic events in epilepsy outpatients are a promising tool for patients and physicians dealing with absence epilepsy. Albeit the small size of the EEG-device, some children still complained about the obtrusive nature of the device. We aim at developing less obtrusive though still very efficient devices, e.g., hidden in the ear canal or below the skin. Ambulatory EEG setup for very long-term recordings on children with absence seizures.