Different-sized black phosphorus nanosheets with good cytocompatibility and high photothermal performance
Different-sized black phosphorus nanosheets with good cytocompatibility and high photothermal performance
复制标题
不同尺寸的黑磷纳米片具有良好的细胞相容性和高光热性能
DOI：
10.1039/c7ra00160f
复制
发表时间：
2017-01-01
期刊：
影响因子：
3.9
通讯作者：
Yu, Xue-Feng
中科院分区：
文献类型：
--
作者：
Fu, Haidi;Li, Zhibin;Yu, Xue-Feng
黑磷（BP）作为一种新型的二维材料，在生物医学领域的应用引起了人们极大的兴趣。纳米粒子的生物医学性能不仅取决于其性质，还取决于其结构和尺寸。在本研究中，我们成功地制备了三种不同尺寸的BP纳米片，并系统地研究了它们的细胞相容性和光热消融癌细胞的效果。从各种测试中可以明显看出，所有三种BP样品都具有优异的细胞相容性，并且具有大尺寸的BP纳米片具有更好的光热效率用于癌细胞消融。我们的研究结果可能提供了一个新的见解BP的基本细胞性能。
As a new kind of two-dimensional (2D) material, black phosphorus (BP) has attracted explosive interest in biomedical applications. It is well-recognized that the biomedical performances of nanoparticles depend not only on their properties, but also on their structures and dimensions. Here in this study, we successfully prepared three kinds of BP nanosheets with different sizes, then systematically investigated their cytocompatibility and photothermal effects to ablate cancer cells. It is evident from various assays that all the three BP samples have excellent cytocompatibility, and the BP nanosheets with a large size have better photothermal efficiency for cancer cell ablation. Our findings may provide a new insight into the fundamental cyto-performances of BP.