Insights from sequencing fungal and oomycete genomes: What can we learn about plant disease and the evolution of pathogenicity?
Insights from sequencing fungal and oomycete genomes: What can we learn about plant disease and the evolution of pathogenicity?
复制标题
DOI：
10.1105/tpc.107.056663
复制
发表时间：
2007-11-01
期刊：
影响因子：
11.6
通讯作者：
Talbot, Nicholas J.
中科院分区：
文献类型：
--
作者：
Soanes, Darren M.;Richards, Thomas A.;Talbot, Nicholas J.
真菌和卵菌是世界上许多最严重的植物疾病的致病因子，在微生物病原体中是独一无二的，它们能够破坏寄主植物的完整表面，迅速建立感染，对大规模农业生产造成灾难性后果。在许多腐养真菌和共生真菌物种中，引起植物疾病的能力并不是一个共同的特征，但它是一个非常普遍的特征，发生在整个真菌王国（James et al., 2006）。发表的最近,已经有很多研究描述了一套不同的真菌和卵菌的基因组序列(表1),其中包括发表在这期的植物细胞(羽根et al ., 2007),这提供了一个机会回顾所学到目前为止从测序的基因组致病性和独立生存的真菌,也期待的质量基因组序列信息生成可能会在未来几年。低成本、高通量DNA测序技术和大规模功能基因组学在真核植物病原体中的应用将为其生物学和致病性进化提供新的见解。
Fungi and oomycetes are the causal agents of many of the world’s most serious plant diseases and are unique among the microbial pathogens in being able to breach the intact surfaces of host plants, rapidly establishing infections that can have disastrous consequences for large-scale agricultural production. The ability to cause plant disease is not a common trait among the many saprotrophic and mutualistic fungal species, but it is a very widespread one, occurring throughout the fungal kingdom (James et al., 2006). Recently, there have been a number of studies published describing the genome sequences of a diverse set of fungi and oomycetes (Table 1), including one published in this issue of The Plant Cell (Hane et al., 2007), and this provides an opportunity to review what we have learned so far from sequencing the genomes of pathogenic and free-living fungi and also to look forward to the mass of genome sequence information that is likely to be generated in the next few years. The deployment of low-cost, high-throughput DNA sequencing technologies and large-scale functional genomics to eukaryotic plant pathogens will provide new insight into their biology and into the evolution of pathogenicity.