Magnetic fractionation and characterization of magnetic nanoparticles for magnetic particle imaging

Magnetic fractionation and characterization of magnetic nanoparticles for magnetic particle imaging
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DOI:
10.7567/jjap.57.080302
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发表时间:
2018-06
影响因子:
1.5
通讯作者:
Takashi Yoshida;Takuru Nakamura;Oji Higashi;K. Enpuku
Takashi Yoshida;Takuru Nakamura;Oji Higashi;K. Enpuku
中科院分区:
物理与天体物理4区
文献类型:
--
作者:
Takashi Yoshida;Takuru Nakamura;Oji Higashi;K. Enpuku

文献摘要

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我们对Resovist®磁性纳米颗粒(MNPs)进行了磁分馏和表征,用于磁颗粒成像(MPI)。结果表明,可以通过调整分离场来控制分馏MNPs的核心大小。我们还表明,核心尺寸约为27 nm的颗粒最适合MPI应用。为了获得合适核心尺寸和窄尺寸分布的MNPs,我们进行了正负联合分选。在得到的分块MNPs中,用作MPI信号的三次谐波磁化强度是原始样品的2.75倍。
We performed magnetic fractionation and characterization of Resovist® magnetic nanoparticles (MNPs) for use in magnetic particle imaging (MPI). We showed that the core size of the fractionated MNPs can be controlled by adjusting the separation field. We also showed that particles with core size of approximately 27 nm are optimal for MPI applications. To obtain MNPs of an appropriate core size and a narrow size distribution, we performed combined positive and negative fractionation. In the obtained fractionated MNPs, the third harmonic magnetization, which is used as the MPI signal, was 2.75 times as large as that of the original sample.