Intervertebral focal surgery for the treatment of non-contiguous multifocal spinal tuberculosis
Intervertebral focal surgery for the treatment of non-contiguous multifocal spinal tuberculosis
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DOI：
10.1007/s00264-011-1478-1
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发表时间：
2012-07-01
影响因子：
2.7
通讯作者：
Niu, Ning-Kui
中科院分区：
文献类型：
--
作者：
Shi, Jian-Dang;Wang, Zi-Li;Niu, Ning-Kui
本研究旨在评价椎间局灶性手术通过彻底清创、畸形矫正、植骨融合、内固定治疗非连续多灶性脊柱结核的临床疗效。 2000年1月至2007年1月收治的29例非连续性多灶性脊柱结核患者均采用椎间局灶性手术治疗。 29例63个病灶，平均每例2.2个病灶，受累椎体146个，平均每个病灶2.3个椎体。 3例两病灶间有1个正常椎间盘，26例两病灶间有2个及以上正常椎间盘。所有病例平均随访5年。术后脊柱后凸平均矫正率为 67.7%。最终随访时观察到平均矫正损失率为 8.2%。 27例患者平均5.8个月血沉、C反应蛋白恢复正常，术后5个月即可观察到骨愈合。 11例神经损伤末次随访恢复至E级。对非连续多灶性脊柱结核患者采用椎间病灶彻底清创、畸形矫正、植骨融合、内固定手术可行、有效。
The purpose of this study was to assess the clinical efficacy of intervertebral focal surgery by complete debridement, deformity correction, graft fusion, and internal fixation for patients with non-contiguous multifocal spinal tuberculosis.A total of 29 cases with non-contiguous multifocal spinal tuberculosis admitted to the hospital from January 2000 to January 2007 were treated by intervertebral focal surgery. There were 63 foci in 29 cases, averaging 2.2 foci per case, and 146 affected vertebral bodies, averaging 2.3 vertebral bodies per focus. Three cases had one normal intervertebral disc between two foci, and the other 26 cases had two or more normal intervertebral discs between two foci.All cases were followed-up for an average of five years. The kyphosis showed a mean correction rate of 67.7% after surgery. A mean loss rate of correction of 8.2% was observed at the final follow-up. The levels of erythrocyte sedimentation rate and C-reactive protein returned to normal in 27 cases on average at 5.8 months and bone union could be observed at five months after surgery. Eleven cases with nerve damage recovered to E grade at the final follow-up.Intervertebral focal surgery by complete debridement, deformity correction, graft fusion, and internal fixation for patients with non-contiguous multifocal spinal tuberculosis was feasible and effective.