Clinical correlates of mind wandering in adults with ADHD
Clinical correlates of mind wandering in adults with ADHD
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DOI：
10.1016/j.jpsychires.2019.06.012
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发表时间：
2019-10-01
影响因子：
4.8
通讯作者：
Faraone, Stephen V.
中科院分区：
文献类型：
--
作者：
Biederman, Joseph;Lanier, Jane;Faraone, Stephen V.
本研究的目的是调查ADHD患者走神的患病率和临床相关性。对255名连续转诊的18至55岁的ADHD成人进行了评估。受试者完成了人口统计学访谈、心智游荡问卷（MWQ）、ADHD评定量表（ADHD RS）、执行功能行为评定量表-成人版（BRIEF-A）、社会反应量表-第二版（SRS-2）成人自我报告表、成人自我报告（ASR）、巴克利情绪失调量表、生活质量满意度问卷（Q-LES-Q）。我们使用受试者操作特征（ROC）曲线来确定MWQ的最佳截止值，以将患者分为高水平和低水平的走神，并比较两组之间的人口统计学和临床特征。根据MWQ总分>=或<24，受试者通过ROC分析分别被归类为具有高水平（N = 127）和低水平（N = 128）的走神。与低水平走神的被试相比，高水平走神的被试有更多的注意力不集中和多动症状（所有p <0.001），通过BRIEF-A测量的执行功能更差，平均受损程度更高（所有p = 65）（所有p < 0.005）在子量表和复合ASR量表上，（p < 0.001），生活质量评分受损较多。高水平的走神在患有ADHD的成年人中很普遍，并且与更严重的ADHD症状、更多的执行功能缺陷、更多的情绪失调、更高水平的相关精神病理学和更多的生活质量受损相关。
The objective of this study was to investigate the prevalence and clinical correlates of ADHD patients with mind wandering. 255 consecutively referred 18- to 55-year-old adults of both sexes with ADHD were assessed. Subjects completed a demographic interview, the Mind Wandering Questionnaire (MWQ), the ADHD Rating Scale (ADHD RS), the Behavior Rating Inventory of Executive Function - Adult Version (BRIEF-A), the Social Responsiveness Scale - Second Edition (SRS-2) Adult Self-Report Form, the Adult Self-Report (ASR), the Barkley Emotional Dysregulation Scale, and the Quality of Life Enjoyment & Satisfaction Questionnaire (Q-LES-Q). We used receiver operator characteristic (ROC) curves to identify the optimal cut-off on the MWQ to categorize patients as having high-versus low-level mind wandering and compared demographic and clinical characteristics between the two groups. Participants were categorized by ROC analysis as having high- (N = 127) and low-level (N = 128) mind wandering based on an MWQ total score >= or < than 24, respectively. Compared with low-level mind wandering participants, those with high-level mind wandering had significantly more Inattentive and Hyperactive symptoms (all p < 0001), worse executive functioning as measured by the BRIEF-A, more impaired mean (all p = 65) (all p < 0.005) on subscales and composite ASR scales, more impaired scores on the Barkley Emotional' Dysregulation Scale (p < 0.001), and more impaired quality of life scores. High-level mind wandering is prevalent in adults with ADHD and is associated with more severe ADHD symptoms, more executive function deficits, more emotional dysregulation, higher levels of associated psychopathology, and more impaired quality of life.