IS GASTRIN RELEASING PEPTIDE MAMMALIAN BOMBESIN

IS GASTRIN RELEASING PEPTIDE MAMMALIAN BOMBESIN
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DOI:
10.1016/0024-3205(80)90453-1
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发表时间:
1980-01-01
期刊:
影响因子:
6.1
通讯作者:
RIVIER, J
RIVIER, J
中科院分区:
医学2区
文献类型:
--
作者:
BROWN, M;MARKI, W;RIVIER, J

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哺乳动物胃泌素释放肽,类似于蛙皮蛙皮素,降低体温,增加肾上腺素和葡萄糖的血浆水平。两种肽在大鼠中产生刻板的抓挠行为。对这些肽的生物反应的相似性和它们共同的C-末端十肽同源性支持胃泌素释放肽是哺乳动物铃蟾肽的概念。
Mammalian gastrin releasing peptide, similar to frog skin bombesin lowers body temperature and increases plasma levels of epinephrine and glucose. Both peptides produce stereotypic scratching behavior in rats. Similarity of biological responses to these peptides and their common C-terminal decapeptide homology supports the concept that gastrin releasing peptide is a mammalian bombesin.