Guideline for the diagnosis and treatment of scabies in Japan (second edition)
Guideline for the diagnosis and treatment of scabies in Japan (second edition)
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DOI：
10.1111/j.1346-8138.2008.00491.x
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发表时间：
2008-06-01
影响因子：
3.1
通讯作者：
Wada, Yasuo
中科院分区：
文献类型：
--
作者：
Ishii, Norihisa;Asahina, Akihiko;Wada, Yasuo
该指南由日本皮肤病协会编写，以确保疥疮的正确诊断和治疗，因为2006年8月在健康保险下可提供口服疗法，其临床使用预计将增加。为了做出正确的诊断，应考虑以下三点：（i）临床症状;（ii）螨（疥螨）的检测;和（iii）流行病学症状。如果通过显微镜或皮肤镜等鉴定出螨或卵，则确诊。局部硫制剂，只有有限的用处，是唯一可用的局部药物批准的健康保险覆盖治疗疥疮。目前临床上也使用克罗米通、苯甲酸苄酯和六氯化γ苯。重要的是将这些应用于全身，包括手，手指和生殖器。伊维菌素的剂量为单次口服给药。约200 μ g/kg体重，餐前用水。如果出现新的特异性病变或检测到螨，则考虑给予第二剂。对于治疗结痂性疥疮，口服伊维菌素和外用制剂同时给药是必要的。一些安全有效的外用药物制剂需要获得医疗保险的批准。
The guideline has been prepared by the Japanese Dermatological Association to ensure proper diagnosis and treatment of scabies, as oral therapy became available on August 2006 under health insurance and its clinical use was expected to increase. For making a proper diagnosis, the following three points should be taken into consideration: (i) clinical symptoms; (ii) detection of the mite (Sarcoptes scabiei); and (iii) epidemiological symptoms. The diagnosis is confirmed if the mites or eggs are identified by microscopy or dermoscopy and so forth. Topical sulfur preparations, with only limited usefulness, are the only available topical drugs approved by health insurance coverage for treating scabies. Currently, crotamiton, benzyl benzoate and gamma-benzene hexachloride are also used clinically. It is important to apply these to the whole-body, including hands, fingers and genitals. The dose for ivermectin is a single administration p.o. of approximately 200 mu g/kg bodyweight with water before a meal. Administration of a second dose is considered, if new specific lesions develop or the mites are detected. For treating crusted scabies, concomitant administration of oral ivermectin and the topical preparation is necessary. Some safe and useful topical drug preparations are needed to be approved by health insurance.