Inflammation and retinopathy of prematurity.

Inflammation and retinopathy of prematurity.
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DOI:
10.1111/j.1651-2227.2010.01836.x
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发表时间:
2010-07
期刊:
Acta paediatrica (Oslo, Norway : 1992)
影响因子:
--
通讯作者:
Dammann O
Dammann O
中科院分区:
其他
文献类型:
--
作者:
Dammann O

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早产儿视网膜病变(ROP)是一种视网膜血管增生性疾病,主要发生于极早产儿[1]。 ROP 儿童的长期视力结果包括一系列视力障碍的风险显着增加 [2]。了解 ROP 的病因和发病机制对于设计预防和治疗这种潜在致残疾病的策略至关重要。不到十年前,一项综述包括这样的说法:“只有低出生体重、低胎龄和分娩后补充氧疗始终与疾病相关”[3]。尽管其他人认识到其他因素可能很重要,包括维生素 E 水平不足、吲哚美辛治疗动脉导管未闭、高碳酸血症、产妇使用阿司匹林、输血和血液制品或需要此类输血,但仍做出了这一声明 [4]。
Retinopathy of prematurity (ROP) is a disorder of retinal vasoproliferation that occurs mainly in extremely preterm infants [1]. The long-term visual outcome among children with ROP includes a prominently increased risk of a range of visual disabilities [2]. Understanding the etiology and pathogenesis of ROP is crucial for the design of strategies to prevent and treat this potentially disabling disease.Less than a decade ago, one review included the statement “only low birth weight, low gestational age, and supplemental oxygen therapy following delivery have been consistently associated with disease”[3]. This statement was made despite the recognition by others that other antecedents might be important, including insufficient levels of vitamin E, indomethacin treatment for patent ductus arteriosus, hypercapnia, maternal aspirin use, and transfusion of blood and blood products or the need for such transfusions [4].
DOI: 10.1016/j.clp.2008.07.011
发表时间: 2008-12
影响因子: 2.1
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