Hippocampal coupling with cortical and subcortical structures in the context of memory consolidation
Hippocampal coupling with cortical and subcortical structures in the context of memory consolidation
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DOI：
10.1016/j.nlm.2018.04.004
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发表时间：
2019-04-01
影响因子：
2.7
通讯作者：
McNaughton, Bruce L.
中科院分区：
文献类型：
--
作者：
Skelin, Ivan;Kilianski, Scott;McNaughton, Bruce L.
记忆巩固是一个渐进的过程，通过这个过程，情景记忆被纳入长期的“语义”表征。它可能涉及在非快速眼动睡眠期间编码最近经历的神经活动的重新激活。记忆巩固的一个关键先决条件是海马体和皮质/皮质下结构之间的再激活事件的精确协调，通过这些结构之间的局部场电位（LFP）振荡（慢振荡、睡眠纺锤波和尖波/波纹）的耦合来促进。我们回顾了迅速扩大的文献中的定性和定量方面的海马振荡和神经元耦合与皮层/皮层下结构的记忆激活的背景下。海马体和皮质/皮质下结构中的再激活与尖波/波纹紧密耦合。海马皮质/皮质下耦合是丰富的维度和这个维度可能被低估，由于目前的方法的局限性。
Memory consolidation is a gradual process through which episodic memories become incorporated into long-term 'semantic' representations. It likely involves reactivation of neural activity encoding the recent experience during non-REM sleep. A critical prerequisite for memory consolidation is precise coordination of reactivation events between the hippocampus and cortical/subcortical structures, facilitated by the coupling of local field potential (LFP) oscillations (slow oscillations, sleep spindles and sharp wave/ripples) between these structures. We review the rapidly expanding literature on the qualitative and quantitative aspects of hippocampal oscillatory and neuronal coupling with cortical/subcortical structures in the context of memory reactivation. Reactivation in the hippocampus and cortical/subcortical structures is tightly coupled with sharp wave/ripples. Hippocampal-cortical/subcortical coupling is rich in dimensionality and this dimensionality is likely underestimated due to the limitations of the current methodology.