Trends in Outcomes, Financial Burden, and Mortality for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) in the United States from 2002 to 2010.
Trends in Outcomes, Financial Burden, and Mortality for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) in the United States from 2002 to 2010.
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DOI：
10.1080/15412555.2016.1199669
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发表时间：
2017-03
期刊：
影响因子：
2.2
通讯作者：
Soubani AO
中科院分区：
文献类型：
--
作者：
Jinjuvadia C;Jinjuvadia R;Mandapakala C;Durairajan N;Liangpunsakul S;Soubani AO
慢性阻塞性肺疾病（COPD）是造成巨大经济和社会负担的原因。我们使用国家住院患者样本（NIS）数据库（2002年至2010年）评估COPD急性加重住院的时间趋势，并确定其结局和经济影响。纳入了年龄≥ 18岁的个体。通过ICD-9代码采集因COPD急性加重的主要诊断而住院的受试者和因其他原因入院但基础疾病为COPD急性加重（次要诊断）的受试者。确定住院结局和住院时间。采用多变量logistic回归分析确定住院患者死亡率的独立预测因子。2002年，COPD急性加重相关住院病例占所有住院病例的近3.31%。这与2010年相比没有显著变化（3.43%，p=0.608）。然而，继发性诊断为COPD的住院率增加。老年白色患者占住院的大部分。医疗保险是大多数住院的主要支付来源（73%-75%）。住院死亡率从2002年的4.8%显著下降到2010年的3.9%（斜率为-0.096，p<.001）。同样，平均住院时间也显著减少，从2002年的6.4天减少到2010年的6.0天（斜率为-0.042，p<.001）。尽管如此，住院费用从2002年的22 187美元大幅增加到2010年的38 455美元。然而，财政负担多年来一直在增加。
Chronic obstructive pulmonary disease (COPD) is the cause of substantial economic and social burden. We evaluated the temporal trends of hospitalizations from acute exacerbation of COPD and determine its outcome and financial impact using the National Inpatient Sample (NIS) databases (2002 to 2010). Individuals with age ≥ 18 years were included. Subjects who were hospitalized with primary diagnosis of COPD exacerbation and those who were admitted for other causes; but had underlying acute exacerbation of COPD (secondary diagnosis) were captured by ICD-9 codes. The hospital outcomes and length of stay were determined. Multivariate logistic regression was used to identify independent predictors of inpatient mortality. Overall acute exacerbation of COPD related hospitalizations accounted for nearly 3.31% of all hospitalizations in year 2002. This did not change significantly to year 2010 (3.43%, p=0.608). However, there was an increase in hospitalization with secondary diagnosis of COPD. Elderly white patients accounted for most of the hospitalizations. Medicare was the primary payer source for most of the hospitalizations (73%–75%). There was a significant decrease in inpatient mortality from 4.8% in 2002 to 3.9% in 2010 (slope −0.096, p<.001). Similarly, there was significant decrease in average length of stay from 6.4 days in 2002 to 6.0 days in 2010 (slope −0.042, p<.001). Despite this the hospitalization cost was increased substantially from $22,187 in 2002 to $38,455 in 2010. However, financial burden has increased over the years.
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影响因子：
168.9
作者：
Calverley, P;Pauwels, R;Maden, C
通讯作者：
Maden, C
影响因子：
--
作者：
Patil, SP;Krishnan, JA;Diette, GB
通讯作者：
Diette, GB
DOI：
10.1164/rccm.201204-0596pp
发表时间：
2013-02-15
影响因子：
24.7
作者：
Vestbo, Jorgen;Hurd, Suzanne S.;Rodriguez-Roisin, Roberto
通讯作者：
Rodriguez-Roisin, Roberto
影响因子：
9.6
作者：
Hilleman, DE;Dewan, N;Friedman, M
通讯作者：
Friedman, M
影响因子：
24
作者：
Blecker, Saul;Paul, Margaret;Taksler, Glen;Ogedegbe, Gbenga;Katz, Stuart
通讯作者：
Katz, Stuart