FEEDING CYCLES ENTRAIN CIRCADIAN-RHYTHMS OF LOCOMOTOR-ACTIVITY IN CS MICE BUT NOT IN C57BL/6J MICE

FEEDING CYCLES ENTRAIN CIRCADIAN-RHYTHMS OF LOCOMOTOR-ACTIVITY IN CS MICE BUT NOT IN C57BL/6J MICE
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DOI:
10.1016/0031-9384(89)90146-7
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发表时间:
1989-02-01
影响因子:
2.9
通讯作者:
MANO, T
MANO, T
中科院分区:
医学3区
文献类型:
--
作者:
ABE, H;KIDA, M;MANO, T

文献摘要

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在连续微弱红灯(LLdim)照射下,观察CS和C57BL/6J小鼠每天固定时间2小时的周期性限制性喂养(RF)对运动活动昼夜节律的影响。在C57BL/6J小鼠中,自由奔跑节律不受射频时间表的影响,尽管在食物获取期之前观察到预期行为。另一方面,CS小鼠的自由奔跑节律确实遵循RF时间表,表现出预期行为。在两个品系中,没有一个对照动物的自由奔跑节律表现出与RF性能同时发生的周期性干扰所造成的任何影响。这些结果表明,CS小鼠的昼夜节律起搏器与食物可携带振荡器(FEO)偶联,但在C57BL/6J小鼠中可能不存在这种偶联,或者这种偶联很弱。
The effects of periodic, restricted feeding (RF) for two hours at a fixed time of day on the circadian rhythms of locomotor activity were examined in CS and C57BL/6J mice, kept under continuous dim, red lights (LLdim). In C57BL/6J mice, free-running rhythms were not affected by an RF schedule, although anticipatory behavior prior to the food access period was observed. On the other hand, the free-running rhythms of CS mice did entrain to an RF schedule, exhibiting anticipatory behavior. The free-running rhythms of none of the control animals in either strain exhibited any effects resulting from the periodic disturbances occurring concurrently with the performance of RF. These results indicate that the circadian pacemaker couples with the food entrainable oscillator (FEO) in CS mice, but that such coupling may not exist, or may be very weak, in C57BL/6J mice.