Epidemiology of 2009 Pandemic Influenza A (H1N1) Deaths in the United States, April-July 2009
Epidemiology of 2009 Pandemic Influenza A (H1N1) Deaths in the United States, April-July 2009
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DOI：
10.1093/cid/ciq022
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发表时间：
2011-01-01
影响因子：
11.8
通讯作者：
Finelli, Lyn
中科院分区：
文献类型：
--
作者：
Fowlkes, Ashley L.;Arguin, Paul;Finelli, Lyn
2009年春季，甲型H1N1流感病毒（pH 1 N1）在全球范围内迅速传播。为了描述美国pH 1 N1相关死亡的地理分布和患者特征，疾病控制和预防中心要求卫生部门提供2009年4月17日至7月23日报告的所有实验室确认的pH 1 N1死亡的信息。数据收集使用医疗图表，体检报告，死亡证明。共确定了377例pH 1 N1相关死亡，死亡率为每10万人0.12例死亡。活动在地理上是局部的，死亡率最高的是夏威夷、纽约和犹他州。76%的死亡发生在18-65岁的人中，9%发生在≥ 65岁的人中。据报告，78%的死亡与基础疾病有关：成人慢性肺病（39%）和儿童神经系统疾病（54%）。与pH 1 N1相关的总体死亡率较低;然而，大多数死亡发生在年龄< 65岁且有基础疾病的人群中。
During the spring of 2009, pandemic influenza A (H1N1) virus (pH1N1) was recognized and rapidly spread worldwide. To describe the geographic distribution and patient characteristics of pH1N1-associated deaths in the United States, the Centers for Disease Control and Prevention requested information from health departments on all laboratory-confirmed pH1N1 deaths reported from 17 April through 23 July 2009. Data were collected using medical charts, medical examiner reports, and death certificates. A total of 377 pH1N1-associated deaths were identified, for a mortality rate of .12 deaths per 100 000 population. Activity was geographically localized, with the highest mortality rates in Hawaii, New York, and Utah. Seventy-six percent of deaths occurred in persons aged 18-65 years, and 9% occurred in persons aged >= 65 years. Underlying medical conditions were reported for 78% of deaths: chronic lung disease among adults (39%) and neurologic disease among children (54%). Overall mortality associated with pH1N1 was low; however, the majority of deaths occurred in persons aged < 65 years with underlying medical conditions.