A comparison of thoracoscopic talc insufflation, slurry, and mechanical abrasion pleurodesis
A comparison of thoracoscopic talc insufflation, slurry, and mechanical abrasion pleurodesis
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DOI：
10.1378/chest.111.2.442
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发表时间：
1997-02-01
期刊：
影响因子：
9.6
通讯作者：
Kapelanski, D
中科院分区：
文献类型：
--
作者：
Colt, HG;Russack, V;Kapelanski, D
本研究的目的是比较4种不同胸膜融合术对10只狗的解剖和组织病理学结果。每只动物被随机分配接受以下两种胸膜切除术方法：胸腔镜下滑石粉注入（粉末）、滑石粉浆液给药、有限开胸术局部纱布磨损和胸腔镜下使用市售胸膜研磨机机械磨损。动物在胸膜切除术后30天死亡。尸检时，通过评估每个胸膜腔和肺的大体外观（胸膜切除术评分）和确定粘连形成的程度（闭塞等级）来对胸膜切除术的疗效进行分级，从最具粘连形成代表性的区域获得胸膜和肺活检标本进行组织病理学评估，滑石粉胸膜切除术评分（从0到4分）为3.0+/-0.7 (p
The purpose of this study was to compare the anatomic and histopathologic results of four different methods of pleurodesis in 10 dogs. Each animal was randomly assigned to receive two of the following methods of pleurodesis: thoracoscopic talc insufflation (poudrage), talc slurry administration, focal gauze abrasion by limited thoracotomy, and mechanical abrasion by thoracoscopy using a commercially available pleural abrader, Animals were killed 30 days after pleurodesis. At autopsy, the efficacy of pleurodesis was graded by evaluating the gross appearance of each pleural cavity and lung (pleurodesis score), and by determining the extent of adhesion formation (obliteration grade), Pleural and lung biopsy specimens were obtained from the areas most representative of adhesion formation for histopathologic evaluation, Pleurodesis scores (on a scale of 0 to 4) were 3.0+/-0.7 for talc poudrage (p