Gender differences in visual discrimination by rats in response to malnutrition of varying durations.
Gender differences in visual discrimination by rats in response to malnutrition of varying durations.
复制标题
大鼠对不同持续时间的营养不良反应的视觉辨别的性别差异。
DOI：
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发表时间：
1980
影响因子：
2.2
通讯作者：
M. Manes
中科院分区：
文献类型：
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作者：
J. Galler;M. Manes
在3个月龄时通过Lashley程序测试戴帽大鼠的视觉辨别。研究使用了三组大鼠：有20代蛋白质缺乏史的大鼠，有一代蛋白质缺乏史的大鼠，以及营养良好的对照组。两个营养不良组的两种性别的生长迟缓程度相似。在代际营养不良的雌性动物中观察到视觉辨别缺陷，但在单代营养不良的雌性动物中没有观察到视觉辨别缺陷。隔代和单代营养不良的男性在视觉识别方面表现出相同的缺陷。这些研究结果表明，雌性大鼠的性能受损后，只有长期暴露于营养不良，而男性是脆弱的，经过较短的时间。
Visual discrimination of hooded rats was tested at 3 months of age by a Lashley procedure. Three groups of rats were used: those with histories of protein deprivation for up to 20 generations, those with protein deprivation for a single generation, and well-nourished controls. Growth retardation was present to a similar degree in both genders of the 2 malnourished groups. Deficits in visual discrimination were observed in female animals with intergenerational malnutrition, but not in females with single-generation malnutrition. Males with intergenerational and single-generation malnutrition showed equal deficits in visual discrimination. These findings demonstrate that the performance of female rats is impaired only after prolonged exposure to malnutrition, whereas males are vulnerable after shorter periods.