Synthesis of Amaryllidaceae alkaloids, siculine, oxocrinine, epicrinine, and buflavine
Synthesis of Amaryllidaceae alkaloids, siculine, oxocrinine, epicrinine, and buflavine
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DOI：
10.1016/j.tet.2004.03.087
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发表时间：
2004-05-24
期刊：
影响因子：
2.1
通讯作者：
Node, M
中科院分区：
文献类型：
--
作者：
Kodama, S;Takita, H;Node, M
利用去甲颠茄碱衍生物的分子内对-对'联苯酚偶联反应，合成了三个石蒜烷型生物碱。此外，还以对-对'联苯酚偶联和二烯酮-苯酚重排反应为关键步骤合成了黄秋葵素。(C)2004 Elsevier Ltd.保留所有权利。
Three crinane type of alkaloids isolated from Amaryllidaceae family were synthesized by taking advantage of the PIFA-mediated intramolecular p-p' diphenol coupling reaction of norbelladine derivatives. Furthermore, buflavine was also prepared by using the p-p' diphenol coupling followed by dienone-phenol rearrangement as a key step. (C) 2004 Elsevier Ltd. All rights reserved.