AGED VENOUS THROMBI - RADIOIMMUNOIMAGING WITH FIBRIN-SPECIFIC MONOCLONAL-ANTIBODY

AGED VENOUS THROMBI - RADIOIMMUNOIMAGING WITH FIBRIN-SPECIFIC MONOCLONAL-ANTIBODY
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DOI:
10.1148/radiology.162.2.3797675
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发表时间:
1987-02-01
期刊:
影响因子:
19.7
通讯作者:
URRUTIA, E
URRUTIA, E
中科院分区:
医学1区
文献类型:
--
作者:
ROSEBROUGH, SF;GROSSMAN, ZD;URRUTIA, E

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已有报道用人类和狗纤维蛋白特异性的鼠单克隆抗体对新鲜的犬静脉血栓进行放射免疫成像。据报道,注射抗体时 1、3 和 5 天的犬深静脉血栓成功成像。所有狗的图像均为阳性,纤维蛋白特异性抗体的摄取与新鲜血栓相当。
Radioimmunoimaging of fresh canine venous thrombi with a murine monoclonal antibody specific for human and dog fibrin has been reported. Successful imaging of canine deep venous thrombi 1, 3, and 5 days old at the time of antibody injection is reported. Images were positive in all dogs, and the uptake of fibrin-specific antibody was equivalent to that of fresh thrombi.