Food-Borne Clenbuterol May Have Potential for Cardiovascular Effects with Chronic Exposure (Commentary)

Food-Borne Clenbuterol May Have Potential for Cardiovascular Effects with Chronic Exposure (Commentary)
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DOI:
10.1081/clt-100105153
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发表时间:
2001-01
期刊:
Journal of Toxicology: Clinical Toxicology
影响因子:
--
通讯作者:
T. Y. Chan
T. Y. Chan
中科院分区:
其他
文献类型:
--
作者:
T. Y. Chan

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克伦特罗是一种选择性β2 (β2)-肾上腺素能激动剂,可以增加肌肉质量,减少脂肪含量,并已被用作牲畜的生长促进剂(1,2)。在摄入受瘦肉精污染的牛肉、猪肉、小牛肉和其他动物部位后发生的急性β-肾上腺素能中毒已经得到了很好的描述,最近也有报道(3)。从理论上讲,食源性盐酸克仑特罗有可能引起慢性心脏毒性。
Clenbuterol, a selective beta2 (β2)-adrenergic agonist, can increase muscle mass and reduce fat content, and has been used as a growth-promoter in livestock (1,2). Acute β-adrenergic poisoning following the ingestion of clenbuterol-contaminated beef, pork, veal, and other animal parts has been well-described and recently reviewed (3). There is theoretically a potential for chronic cardiac toxicity from food-borne clenbuterol.