RESTENOSIS AFTER SUCCESSFUL PERCUTANEOUS TRANS-LUMINAL CORONARY ANGIOPLASTY - SERIAL ANGIOGRAPHIC FOLLOW-UP OF 229 PATIENTS
RESTENOSIS AFTER SUCCESSFUL PERCUTANEOUS TRANS-LUMINAL CORONARY ANGIOPLASTY - SERIAL ANGIOGRAPHIC FOLLOW-UP OF 229 PATIENTS
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DOI：
10.1016/s0735-1097(88)80046-9
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发表时间：
1988-09-01
影响因子：
24
通讯作者：
OHISHI, H
中科院分区：
文献类型：
--
作者：
NOBUYOSHI, M;KIMURA, T;OHISHI, H
为了进一步了解冠状动脉再狭窄的时间模式和机制，对229例患者进行了前瞻性血管造影随访，分别在经皮冠状动脉腔内成形术成功后的第1天和1、3、6个月和1年。冠状动脉狭窄的定量测量是通过电影密度分析实现的。1个月、3个月、6个月和1年时的再狭窄率分别为12.7%、43.0%、49.4%和52.5%。在219例随访患者中，3个月时，平均狭窄直径为1.91 . ±. 0.53冠状动脉成形术后即刻，1.72 ±. 0.52第1天，1.86 ±. mm。0.58 1个月时为1.43 ±. 0.67 3个月时mm。在149例随访患者中，6个月时，平均狭窄直径为1.66 ±。0.58 3个月时为1.66 ±. 0.62 6个月时mm。73例随访1年，平均狭窄直径为1.65 ± 0.05。0.56 6个月时为1.66 ±. 0.57 1年时mm。因此，狭窄直径在冠状动脉成形术后1个月至3个月显著降低，此后达到平台期。总之，冠状动脉成形术后1 - 3个月内再狭窄最常见，3个月后很少发生。
To further understand the temporal mode and mechanisms of coronary restenosis, 229 patients were studied by prospective angiographic follow-up on day 1 and at 1, 3 and 6 months and 1 year after successful percutaneous transluminal coronary angioplasty. Quantitative measurement of coronary stenosis was achieved by cinevideodensitometric analysis. Actuarial restenosis rate was 12.7% at 1 month, 43.0% at 3 months, 49.4% at 6 months and 52.5% at 1 year. In 219 patients followed up for .gtoreq. 3 months, mean stenosis diameter was 1.91 .+-. 0.53 mm immediately after coronary angioplasty, 1.72 .+-. 0.52 mm on day 1, 1.86 .+-. 0.58 mm at 1 month and 1.43 .+-. 0.67 mm at 3 months. In 149 patients followed up for .gtoreq. 6 months, mean stenosis diameter was 1.66 .+-. 0.58 mm at 3 months and 1.66 .+-. 0.62 mm at 6 months. In 73 patients followed up for 1 year, mean stenosis diameter was 1.65 .+-. 0.56 mm at 6 months and 1.66 .+-. 0.57 mm at 1 year. Thus, stenosis diameter decreased markedly between 1 month and 3 months after coronary angioplasty and reached a plateau thereafter. In conclusion, restenosis is most prevalent between 1 and 3 months and rarely occurs beyond 3 months after coronary angioplasty.