Influenza-Associated Hospitalizations, Singapore, 2004-2008 and 2010-2012
Influenza-Associated Hospitalizations, Singapore, 2004-2008 and 2010-2012
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DOI：
10.3201/eid2010.131768
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发表时间：
2014-10-01
影响因子：
11.8
通讯作者：
Cutter, Jeffery
中科院分区：
文献类型：
--
作者：
Ang, Li Wei;Lim, Cindy;Cutter, Jeffery
缺乏对热带地区流感相关住院的研究。为了增加对流感在新加坡影响的了解，我们估计了2004-2008年和2010-2012年期间因肺炎和流感而住院的年龄特异性流感相关患者。2004-2008年期间的住院率为28.3/100 000人年，2010-2012年期间为29.6/100 000人年。年龄特异性流感相关住院率遵循J形模式：≥ 75岁人群和儿童的住院率分别是25-44岁人群的47倍和>26倍。在这2个研究阶段的所有年龄段中，约12%的肺炎和流感住院可归因于流感。在新加坡，因流感而住院的比率和比例相当高，特别是在年幼者和老年人中，这突出表明了疫苗接种在保护高危人群方面的重要性。
Studies of influenza-associated hospitalizations in tropical settings are lacking. To increase understanding of the effect of influenza in Singapore, we estimated the age-specific influenza-associated hospitalizations for pneumonia and influenza during 2004-2008 and 2010-2012. The rate of hospitalization was 28.3/100,000 person-years during 2004-2008 and 29.6/100,000 person-years during 2010-2012. The age-specific influenza-associated hospitalization rates followed a J-shaped pattern: rates in persons >= 75 years of age and in children 47 times and >26 times higher, respectively, than those for persons 25-44 years of age. Across all ages during these 2 study periods, approximate to 12% of the hospitalizations for pneumonia and influenza were attributable to influenza. The rates and proportions of hospitalizations attributable to influenza, particularly among the very young and the elderly, are considerable in Singapore and highlight the importance of vaccination in protecting populations at risk.