Racial differences in factors that influence the willingness to participate in medical research studies
Racial differences in factors that influence the willingness to participate in medical research studies
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DOI：
10.1016/s1047-2797(01)00265-4
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发表时间：
2002-05-01
影响因子：
5.6
通讯作者：
Burmeister, LF
中科院分区：
文献类型：
--
作者：
Shavers, VL;Lynch, CF;Burmeister, LF
目得：医学研究对象中相对缺乏种族/族裔少数群体正受到相当大的关注，因为最近政府要求将其纳入所有人类研究对象。我们研究了种族差异的社会文化障碍的患病率作为一个可能的解释，代表性不足的非洲裔美国人在医学研究study.METHODS：在1998-1999年，共有198名居民的底特律主要大都市统计区（PMSA）参加了一项调查，研究障碍，参与医学研究。卡方检验和Logistic回归分析被用来研究种族之间的关联，有关问题的信任的医学研究人员，并愿意参加医学研究studies.RESULTS：研究结果表明，非洲裔美国人和白人不同，他们愿意参加医学研究。参与医学研究意愿的种族差异主要是由于非裔美国人对医学研究的信任程度较低。非裔美国人的受访者也有点不太愿意参加，如果他们属性的高度重视，以种族的医生在寻求常规的医疗护理，认为少数民族承担大部分的风险，医学研究，如果他们的知识的塔斯基吉研究导致在医学researcher.CONCLUSION的信任程度较低：这些数据重申需要医学研究人员建立信任关系与少数民族社区。研究人员可以开始承认以前对少数民族研究参与者的医疗虐待，讨论他们的具体计划，以确保研究参与者的保护，并解释种族/民族少数群体参与的必要性，包括专门针对或可能导致研究参与者中种族/民族少数群体比例过高的研究。(C)2002年爱思唯尔科学公司All rights reserved.
PURPOSE: The relative absence of racial/ethnic minorities among medical research subjects is receiving considerable attention because of recent government mandates for their inclusion in all human subject re, search. We examined racial differences in the prevalence of sociocultural barriers as a possible explanation for the underrepresentation of African Americans in medical research studies.METHODS: During 1998-1999, a total of 198 residents of the Detroit Primary Metropolitan Statistical Area (PMSA) participated in a survey that examined impediments to participation in medical research studies. Chi square tests and logistic regression analyses were used to examine the association between race, issues related to trust of medical researchers, and the willingness to participate in medical research studies.RESULTS: Study results indicate that African Americans and whites differ in their willingness to participate in medical research. Racial differences in the willingness to participate in a medical research are primarily due to the lower level of trust of medical research among African Americans. African American respondents were also somewhat less willing to participate if they attribute high importance to the race of the doctor when seeking routine medical care, believed that minorities bear most of the risks of medical research, and if their knowledge of the Tuskegee Study resulted in less trust in medical researchers.CONCLUSION: These data reiterate the need for medical researchers to build trusting relationships with minority communities. Researchers can begin by acknowledging the previous medical abuse of minority research participants, discussing their specific plans to assure the protection of study participants, and explaining the need for the participation of racial/ethnic minorities including studies that specifically target or that are likely to result in disproportionate representation of racial/ethnic minorities among study participants. (C) 2002 Elsevier Science Inc. All rights reserved.