Editorial comment to genome-wide transcriptome analysis of fluoroquinolone resistance in clinical isolates of Escherichia coli.
Editorial comment to genome-wide transcriptome analysis of fluoroquinolone resistance in clinical isolates of Escherichia coli.
复制标题
对大肠杆菌临床分离株氟喹诺酮耐药性的全基因组转录组分析的编辑评论。
DOI：
10.1111/j.1442-2042.2012.02996.x
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Zechiedrich,Lynn
中科院分区：
文献类型：
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作者：
Zechiedrich,Lynn
在本文中，作者评论了临床分离的大肠杆菌对氟喹诺酮耐药性的全基因组转录组分析的研究。他表示，研究人员分离了几个导致耐药性的基因，然而，他们关注的是两个特定基因 pspC 和 dam。据了解，pspC蛋白有助于调节相休克蛋白操纵子，dam基因编码甲基化酶。此外，尚未有任何利益冲突的报道。
In this article the author comments on a research conducted on genome-wide transcriptome analysis of fluoroquinolone resistance presented by clinically isolated Escherichia coli. He states that the researchers isolated several genes responsible for the resistance, however, they focused on two specific genes pspC and dam. It is informed that pspC proteins helps in regulation of phase shock protein operon and dam gene encodes methylase. Also, no conflict of interests has been reported.