Proton Pumping ATPases and Diverse Inside-Acidic Compartments
Proton Pumping ATPases and Diverse Inside-Acidic Compartments
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质子泵ATP酶和多种内部酸性隔室
DOI：
10.1002/chin.200436271
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Y. Wada
中科院分区：
文献类型：
--
作者：
M. Futai;G. Sun;Y. Wada
质子转运ATP酶是细胞内重要的能量转换器，它将ATP水解的化学能转化为跨膜质子电化学电势差。本文就F型、V型和P型三大类ATP酶的结构、催化机制和细胞功能作一综述。酸性细胞器和车厢的生理作用进行了讨论。
Proton-translocating ATPases are essential cellular energy converters that transduce the chemical energy of ATP hydrolysis into transmembrane proton electrochemical potential differences. The structures, catalytic mechanism, and cellular functions of three major classes of ATPases including the F-type, V-type, and P-type ATPase are discussed in this review. Physiological roles of the acidic organelles and compartments contained are also discussed.