Cerebral hemodynamics in relation to patterns of collateral flow
Cerebral hemodynamics in relation to patterns of collateral flow
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DOI：
10.1161/01.str.30.7.1432
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发表时间：
1999-07-01
期刊：
影响因子：
8.3
通讯作者：
Viergever, MA
中科院分区：
文献类型：
--
作者：
Kluytmans, M;van der Grond, J;Viergever, MA
Background and Purpose-We sought to investigate the relation between collateral flow via different pathways and hemodynamic parameters measured by dynamic susceptibility contrast-enhanced MRI in patients with severe carotid artery disease.Methods-Dynamic susceptibility contrast-enhanced MRI was performed in 66 patients and 33 control subjects. Patients had severe stenosis (>70%, n=12), unilateral occlusion (n=38), or bilateral occlusion (n=16) of the internal carotid artery (ICA). Cerebripetal flow and collateral flow via the circle of Willis were investigated with MR angiography, Collateral Row via the ophthalmic artery was investigated with transcranial Doppler sonography.Results-Patients with ICA stenosis had well-preserved cerebral perfusion and were in general not dependent on collateral supply. Patients with unilateral ICA occlusion had impaired cerebral perfusion. However, appearance time, peak time, and mean transit time in white matter were less increased in patients with than in patients without collateral flow via the circle of Willis (P
