Physical Activity and Adiposity in a Racially Diverse Cohort of US Infants
Physical Activity and Adiposity in a Racially Diverse Cohort of US Infants
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DOI：
10.1002/oby.22738
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发表时间：
2020-01-16
期刊：
影响因子：
6.9
通讯作者：
Crainiceanu, Ciprian
中科院分区：
文献类型：
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作者：
Benjamin-Neelon, Sara E.;Bai, Jiawei;Crainiceanu, Ciprian
目的生命早期体育活动可能有助于预防肥胖，但对婴儿进行客观量化是具有挑战性的。方法2013 - 2016年对506例婴幼儿进行检查。婴儿在3、6、9和12个月时佩戴加速度计4天。计算每日对数转换的体力活动计数，平均并标准化评估。使用线性混合模型来检验标准化体力活动计数的趋势，以及体力活动与BMI z评分、肩胛下和三头肌皮褶厚度之和与整体肥胖（SS+TR）以及它们与中心性肥胖（SS:TR）的比值之间的关系。结果新生儿中黑人占66%，女性占50%。每增加一次就诊，标准化身体活动计数增加0.23 （CI: 0.18至0.27;P < 0.0001）。这相当于126.3次未经调整的身体活动，或超过3个月的每次访问增加4%。接下来，我们发现标准化体力活动计数（550个未经调整的体力活动计数）增加1个标准差与SS:TR降低0.01 mm相关（95% CI: -0.02至-0.001;P = 0.03）。然而，标准化的体力活动计数与BMI z评分或SS+TR无关。结论：婴儿时期体力活动增加与中枢性肥胖有关。尽管存在局限性，但研究人员应该考虑对婴儿进行客观测量。
Objective Early life physical activity may help prevent obesity, but objective quantification in infants is challenging. Methods A total of 506 infants were examined from 2013 to 2016. Infants wore accelerometers for 4 days at ages 3, 6, 9, and 12 months. Daily log-transformed physical activity counts were computed, averaged, and standardized across assessments. A linear mixed model was used to examine trends in standardized physical activity counts as well as associations between physical activity and BMI z score, sum of subscapular and triceps skinfold thickness for overall adiposity (SS+TR), and their ratio for central adiposity (SS:TR). Results Among infants, 66% were black and 50% were female. For each additional visit, standardized physical activity counts increased by 0.23 (CI: 0.18 to 0.27; P < 0.0001). This translates to 126.3 unadjusted physical activity counts or a 4% increase for each visit beyond 3 months. Next, we found that a 1-SD increase in standardized physical activity counts (550 unadjusted physical activity counts) was associated with a 0.01-mm lower SS:TR (95% CI: -0.02 to -0.001; P = 0.03). However, standardized physical activity counts were not associated with BMI z score or SS+TR. Conclusions Physical activity increased over infancy and was associated with central adiposity. Despite limitations, researchers should consider objective measurement in infants.