Positive affect dimensions and their association with inflammatory biomarkers in patients with chronic heart failure
Positive affect dimensions and their association with inflammatory biomarkers in patients with chronic heart failure
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DOI：
10.1016/j.biopsycho.2012.10.002
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发表时间：
2013-02-01
影响因子：
2.6
通讯作者：
Denollet, Johan
中科院分区：
文献类型：
--
作者：
Brouwers, Corline;Mommersteeg, Paula M. C.;Denollet, Johan
背景资料：方法：采用整体情绪量表（GMS）、积极与消极情绪量表（PANAS）和医院焦虑抑郁量表（HADS）对慢性心力衰竭患者的积极情绪进行评定（N = 210; 67 +/- 9岁，79%为男性）。结果：GMS和PANAS的积极情感维度与较低的平均5 TNFr 2、TNF α和IL-6水平显著相关（P
Background: In cardiac patients positive affect has found to be associated with improved clinical outcomes, with reduced inflammation being one of the potential mechanisms responsible.Methods: Positive affect was assessed using The Global Mood Scale (GMS), Positive and Negative Affect Schedule (PANAS), and Hospital Anxiety and Depression Scale (HADS) in patient with chronic heart failure (N = 210; 67 +/- 9 years, 79% men). Markers of inflammation (TNF alpha, sTNFr1, 5TNFr2, IL-6 and CRP) were measured and averaged at three consecutive time points.Results: The positive affect dimensions of the GMS and PANAS were significantly associated with lower averaged levels of 5TNFr2, TNF alpha and IL-6 (p