Neuroticism, depression and anxiety in takotsubo cardiomyopathy.
Neuroticism, depression and anxiety in takotsubo cardiomyopathy.
复制标题
DOI：
10.1186/s12872-016-0277-4
复制
发表时间：
2016-05-31
影响因子：
2.1
通讯作者：
Østergaard SD
中科院分区：
文献类型：
--
作者：
Christensen TE;Bang LE;Holmvang L;Hasbak P;Kjær A;Bech P;Østergaard SD
Takotsubo心肌病（TTC）导致急性可逆性心力衰竭。先前的研究表明，该综合征与社会抑制，慢性心理压力和焦虑抑郁症等特征有关。本研究的目的是进一步描述TTC患者的关键心理/精神病理学特征。对三组进行了调查：I）2009年10月1日至2014年12月10日期间入院的女性康复后TTC患者，II）年龄、性别和地理位置匹配的ST段抬高性心肌梗死（STEMI）患者，以及III）年龄、性别和地理位置匹配的背景人群。采用WHO-5幸福感指数量表、艾森克神经质量表、抑郁自评量表和症状自评量表中的焦虑分量表进行问卷调查。在230名受邀者中，共有173人（75%）参加了研究。与背景对照组相比，TTC患者的幸福感明显降低，神经质增加，抑郁和焦虑增加。TTC和STEMI患者的幸福感、抑郁和神经质水平相当，但TTC患者的焦虑水平较高。TTC入院时间与精神病理学量表总分呈负相关。TTC患者报告的焦虑水平显著高于STEMI患者和背景对照。然而，与STEMI患者不同，TTC患者在恢复后阶段出现心理改善。这可能是一个安慰TTC患者在急性心理困扰。
Takotsubo cardiomypathy (TTC) causes acute reversible heart failure. Prior studies have indicated that the syndrome is associated with traits such as social inhibition, chronic psychological stress, and anxio-depressive disorders. The objective of this study was to further characterize key psychological/psychopathological traits of patients with TTC. A survey of three groups was conducted: I) Female post-recovery TTC patients admitted between October 1st 2009 and December 10th 2014, II) Age, gender and geographically matched ST-elevation myocardial infarction (STEMI) patients, and III) Age, gender and geographically matched individuals from the background population. The following questionnaires were used in the survey: the WHO-5 Well-Being Index, Eysenck’s Neuroticism Scale, the Major Depression Inventory, and the anxiety subscale of Symptoms Checklist (SCL-90). In total, 173 of 230 invitees (75 %) participated in the study. In comparison to the background controls, TTC patients reported significantly less well-being, more neuroticism, more depression, and more anxiety. The levels of well-being, depression and neuroticism were comparable between TTC and STEMI patients, but the level of anxiety was higher in the TTC patients. There was a negative correlation between the time since TTC admission and the total scores on the psychopathology rating scales. Patients with TTC reported significantly higher anxiety levels compared to both STEMI patients and background controls. However, unlike the STEMI patients, the TTC patients appeared to improve psychologically during the post-recovery phase. This may be a consolation for TTC patients in acute psychological distress.