Meta-analysis of symptom factors in schizophrenia

Meta-analysis of symptom factors in schizophrenia
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DOI:
10.1016/s0920-9964(98)00011-5
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发表时间:
1998-05-25
影响因子:
4.5
通讯作者:
Goldman, RS
Goldman, RS
中科院分区:
医学2区
文献类型:
--
作者:
Grube, BS;Bilder, RM;Goldman, RS

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因素分析和相关分析已被用于表征精神分裂症的症状维度,尽管它们产生了不同的模型。本研究采用荟萃分析对已发表的研究成果进行分析,以确定症状维度的数量和构成。对10项实证研究(汇集n=896项)的数据进行主成分分析,得出三个因素,即“积极的”、“消极的”和“概念上的混乱”。这些发现表明,在评估慢性患者的这些症状的研究中,三因素解决方案是相对稳定的结果,一些症状(孤独症、注意力障碍)不太可能唯一地加载在单一因素上。(C)1998 Elsevier Science B.V.保留所有权利。
Factor and correlational analyses have been used to characterize symptom dimensions in schizophrenia, though they have yielded divergent models. This study used meta-analysis of published work to determine the number and composition of symptom dimensions. Principal components analysis of data from 10 empirical studies (pooled n = 896) yielded three factors, 'positive', 'negative' and 'conceptual disorganization'. The findings suggest that a three-factor solution is a relatively stable outcome of studies assessing these symptoms in chronic patients, and that some symptoms (alogia, attentional impairment) are less likely to load uniquely on a single factor. (C) 1998 Elsevier Science B.V. All rights reserved.