Intestinal helminth infections in HIV-infected patients in Savannakhet after establishment of an HIV registration network in Lao People's Democratic Republic
Intestinal helminth infections in HIV-infected patients in Savannakhet after establishment of an HIV registration network in Lao People's Democratic Republic
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DOI：
10.1186/s41182-019-0142-0
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发表时间：
2019-02-11
影响因子：
4.5
通讯作者：
Fukushima, Takuya
中科院分区：
文献类型：
--
作者：
Kaneshiro, Yukako;Sourinphoumy, Khamphang;Fukushima, Takuya
背景在与中国、越南、柬埔寨、泰国和缅甸接壤的老挝人民民主共和国（PDR），近年来艾滋病毒感染者的数量有所增加。在老挝人民民主共和国诊断出的艾滋病毒感染者登记在一个登记网络中，并接受政府财政支助的抗逆转录病毒疗法。基于登记网络，我们调查了肠道蠕虫感染和合并感染HTLV-1的艾滋病毒感染患者接受早期干预治疗，使用ART在老挝PDR.MethodsThis横断面研究的所有252名艾滋病毒感染患者在沙湾拿吉省医院，位于老挝南部，进行了2018年2月至3月。社会流行病学信息和临床信息从登记网络数据库中收集，并通过向参与者进行问卷调查。肠道蠕虫感染的粪便样本和颗粒凝集抗-HTLV-1抗体在plasma.ResultsThe所有252名参与者的中位年龄为39岁（范围，18-59）的显微镜检查。根据登记网络数据库，有156名（61.9%）HIV感染者的CD 4阳性细胞计数200个细胞/L，146名（57.9%）HIV病毒载量
BackgroundIn Lao People's Democratic Republic (PDR), which borders China, Vietnam, Cambodia, Thailand, and Myanmar, the number of HIV-infected patients has increased in recent years. HIV-infected patients diagnosed in Lao PDR are enrolled in a registration network and receive antiretroviral therapy (ART) covered by governmental financial support. Based on the registration network, we investigated intestinal helminth infections and coinfection with HTLV-1 in HIV-infected patients treated with an early intervention using ART in Lao PDR.MethodsThis cross-sectional study of all 252 HIV-infected patients at Savannakhet Provincial Hospital, located in the southern part of Lao PDR, was conducted between February and March 2018. Socioepidemiological information and clinical information were collected from a registration network database and by questionnaire administered to participants. Microscopic examination of intestinal helminth infections in stool samples and particle agglutination for anti-HTLV-1 antibody in plasma were performed.ResultsThe median age of all 252 participants was 39years old (range, 18-59). Based on the registration network database, there were 156 (61.9%) HIV-infected patients with a CD4-positive cell count 200 cells/L and 146 (57.9%) with an HIV viral load