Neighborhoods and genes and everything in between: understanding adolescent aggression in social and biological contexts.
Neighborhoods and genes and everything in between: understanding adolescent aggression in social and biological contexts.
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DOI：
10.1017/s0954579409000510
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发表时间：
2009
影响因子：
3.3
通讯作者：
Marmorstein NR
中科院分区：
文献类型：
--
作者：
Hart D;Marmorstein NR
探讨了青少年攻击性与邻里关系和遗传特征的关系。对12098名青少年进行了为期1年的纵向跟踪调查，研究了儿童饱和度(人口中15岁以下儿童的比例)、种族异质性、贫困和社区的都市化与青少年攻击性的关系。纵向分析表明，儿童饱和度与攻击性的增加呈正相关，这一发现出现在那些在测试期间住在同一社区的人，以及那些在测试期间搬家的人。在有遗传数据的男性样本中，儿童饱和程度与青少年攻击性的关系受到单胺氧化酶A(MAOA)基因的调节。携带MAOA低活性等位基因的儿童，其攻击性在饱和状态下的退化程度要比高活性等位基因的儿童更为严重。这一结果对理解攻击性和人格障碍的起源和个体发生的意义进行了讨论。
Adolescent aggression was explored in relation to neighborhood and genetic characteristics. Child saturation (the proportion of the population consisting of children under the age of 15), ethnic heterogeneity, poverty, and urbanicity of neighborhoods were examined in relation to adolescent aggression in 12,098 adolescents followed longitudinally for 1 year. Longitudinal analyses indicated that child saturation was positively associated with increases in aggression, with this finding emerging among those living in the same neighborhood at both testing times and those who moved between testing times. In a subsample of males for whom genetic data were available, the relation of child saturation to adolescent aggression was moderated by the monoamine oxidase A (MAOA) gene. The regression of aggression on child saturation was steeper for those with the low activity version of the MAOA allele than among those with the high activity version of the allele. The implications of the results for an understanding of the origins and ontogeny of aggression and personality disorders are discussed.