Enteric Coronavirus Infection in a Juvenile Dromedary (Camelus Dromedarius)
Enteric Coronavirus Infection in a Juvenile Dromedary (Camelus Dromedarius)
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幼年单峰骆驼（Camelus Dromedarius）的肠道冠状病毒感染
DOI：
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发表时间：
2002
影响因子：
1.5
通讯作者：
S. Kapil
中科院分区：
文献类型：
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作者：
A. Wünschmann;R. Frank;Kem Pomeroy;S. Kapil
一例肠道冠状病毒感染在一个6周大的单峰小牛描述。动物腹泻5天，经对症治疗死亡。电镜下在粪便中检测到大量病毒颗粒，直径约140 nm，呈棒状突起。这些特征与冠状病毒一致。2种抗原型II型冠状病毒特异性抗体的免疫组化反应证实了结肠上皮细胞中存在病毒抗原。该动物的死亡归因于中性粒细胞和肺气肿性结肠炎，可能是由梭状芽胞杆菌感染引起的。
A case of an enteric coronavirus infection in a 6-week-old dromedary calf is described. The animal had diarrhea for 5 days and died despite symptomatic treatment. Numerous viral particles, approximately 140 nm in diameter, with club-like projections were detected in the feces by electron microscopy. These characteristics were consistent with a coronavirus. Immunohistochemical reactivity with 2 antigenic group II coronavirus-specific antibodies confirmed the presence of viral antigen in colonic epithelial cells. The death of the animal was attributed to a neutrophilic and emphysematous colitis that likely was caused by an infection with a Clostridium sp.