PGDB: a curated and integrated database of genes related to the prostate
PGDB: a curated and integrated database of genes related to the prostate
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DOI：
10.1093/nar/gkg008
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发表时间：
2003-01-01
影响因子：
14.9
通讯作者：
Dahiya, R
中科院分区：
文献类型：
--
作者：
Li, LC;Zhao, H;Dahiya, R
前列腺基因数据库（PGDB：http：//www.ucsf.edu/pgdb）是与人类前列腺和前列腺疾病相关的基因或基因组位点的策划和整合数据库。目前，PGDB涵盖了涉及前列腺的许多分子和遗传事件的基因，包括基因扩增、突变、总缺失、甲基化、多态性、连锁和过表达，如文献中所发表的。还包括在前列腺中特异性表达的基因，如通过来自表达序列标签（EST）的数据分析和基因表达的系列分析（SAGE）所证明的。数据库中共有165个独特条目。用户可以通过Web界面浏览或查询PGDB。对于每个基因，除了基本的基因信息和与其他数据库的丰富交叉引用外，还提供了包容性和相关的文献参考，以支持将该基因纳入数据库。还提供了从UniGene和SAGEmap数据库计算的详细表达数据。
The Prostate Gene Database (PGDB: http://www.ucsf.edu/pgdb) is a curated and integrated database of genes or genomic loci related to the human prostate and prostatic diseases. Currently, PGDB covers genes involved in a number of molecular and genetic events of the prostate including gene amplification, mutation, gross deletion, methylation, polymorphism, linkage and over-expression, as published in the literature. Genes that are specifically expressed in prostate, as evidenced by analysis of data from expressed sequence tags (ESTs) and serial analysis of gene expression (SAGE), are also included. There are a total of 165 unique entries in the database. Users can either browse or query the PGDB through a web interface. For each gene, in addition to basic gene information and rich cross-references to other databases, inclusive and relevant literature references are provided to support the inclusion of the gene in the database. Detailed expression data calculated from the UniGene and SAGEmap databases are also presented.