Report of a hürthle cell neoplasm in a peripubertal girl.

Report of a hürthle cell neoplasm in a peripubertal girl.
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一名围青春期女孩的 hürthle 细胞肿瘤的报告。

DOI:
10.1089/thy.2006.0214
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发表时间:
2007
期刊:
Thyroid : official journal of the American Thyroid Association
影响因子:
--
通讯作者:
Rosenthal,StephenM
Rosenthal,StephenM
中科院分区:
--
文献类型:
--
作者:
Bremer,AndrewA;Feldman,BrianJ;Iezza,Gioia;Clark,OrloH;Rosenthal,StephenM

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与成人相比,儿童的甲状腺结节很少见。尽管大多数甲状腺结节是良性的,但儿童患者恶变的风险更大。乳头状细胞瘤和滤泡细胞瘤占甲状腺肿瘤的大部分; Hürthle 细胞瘤占不到 5%。尽管不常见,恶性许特勒细胞肿瘤可能比乳头状和滤泡细胞肿瘤更具侵袭性。因此,及时区分甲状腺肿瘤的类型对于预后和治疗具有重要意义。我们描述了一名 12 岁的青春期女孩,她出现右侧甲状腺大结节,随后被诊断为 Hürthle 细胞腺瘤。据我们所知,她代表了最年轻的 Hürthle 细胞肿瘤患者。
Thyroid nodules are rare in children compared to adults. Although most thyroid nodules are benign, the risk of malignancy is greater in pediatric patients. Papillary and follicular cell tumors account for the majority of thyroid neoplasms; Hürthle cell tumors account for less than 5%. Despite being uncommon, malignant Hürthle cell tumors are potentially more aggressive than papillary and follicular cell tumors. Therefore, distinguishing between types of thyroid neoplasms in a timely fashion has implications for prognosis and therapy. We describe a 12-year-old peripubertal girl who presented with a large right-sided thyroid nodule that was subsequently diagnosed as a Hürthle cell adenoma. To our knowledge, she represents the youngest patient with a Hürthle cell neoplasm.
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