STRUCTURE ELUCIDATION OF 2 DIFFERENTIATION INDUCING FACTORS (DIF-2 AND DIF-3) FROM THE CELLULAR SLIME-MOLD DICTYOSTELIUM-DISCOIDEUM

STRUCTURE ELUCIDATION OF 2 DIFFERENTIATION INDUCING FACTORS (DIF-2 AND DIF-3) FROM THE CELLULAR SLIME-MOLD DICTYOSTELIUM-DISCOIDEUM
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DOI:
10.1042/bj2490903
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发表时间:
1988-02-01
影响因子:
4.1
通讯作者:
KAY, RR
KAY, RR
中科院分区:
生物学3区
文献类型:
--
作者:
MORRIS, HR;MASENTO, MS;KAY, RR

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DIF-1 {1-[(3,5-二氯-2,6-二羟基-4-甲氧基)苯基]己-1-酮}的1-戊酮和一氯类似物是诱导盘基网柄霉菌(Dictyosteelicdiscoideum)茎细胞分化的两种内源性分化诱导因子(DIF-2和DIF-3)。这些化合物代表了一类新的效应分子。
Two endogenous differentiation-inducing factors (DIF-2 and DIF-3), which induce stalk-cell differentiation in the cellular slime mould Dictyostelium discoideum, have been identified as the pentan-1-one and monochloro analogues respectively of DIF-1 {1-[(3,5-dichloro-2,6-dihydroxy-4-methyoxy)phenyl]hexan-1-one}. These compounds represent a new chemical class of effector molecules.