Dissolution Chemistry and Biocompatibility of Single-Crystalline Silicon Nanomembranes and Associated Materials for Transient Electronics
Dissolution Chemistry and Biocompatibility of Single-Crystalline Silicon Nanomembranes and Associated Materials for Transient Electronics
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DOI：
10.1021/nn500847g
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发表时间：
2014-06-01
期刊：
影响因子：
17.1
通讯作者：
Rogers, John A.
中科院分区：
文献类型：
--
作者：
Hwang, Suk-Won;Park, Gayoung;Rogers, John A.
单晶硅纳米膜(SiNMS)是一类至关重要的材料，用于高性能形式的电子产品，这些产品在浸泡在水和/或生物流体中时能够完全、可控地溶解，有时被称为一种“瞬时”电子产品。本文报道的结果包括硅纳米管在生物体液和各种水溶液中的水解动力学，通过一系列相关的pH值、离子浓度和温度，以及对掺杂类型和浓度的依赖关系。对硅纳米管和其他暂态电子材料的体外和体内研究表明，它具有生物兼容性和生物再吸收能力，因此有望在活性、可生物降解的电子植入物中得到应用。
Single-crystalline silicon nanomembranes (Si NMs) represent a critically important class of material for high-performance forms of electronics that are capable of complete, controlled dissolution when immersed in water and/or biofluids, sometimes referred to as a type of "transient" electronics. The results reported here include the kinetics of hydrolysis of Si NMs in biofluids and various aqueous solutions through a range of relevant pH values, ionic concentrations and temperatures, and dependence on dopant types and concentrations. In vitro and in vivo investigations of Si NMs and other transient electronic materials demonstrate biocompatibility and bioresorption, thereby suggesting potential for envisioned applications in active, biodegradable electronic implants.