Physiopathology of the cochlear microcirculation.
Physiopathology of the cochlear microcirculation.
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DOI：
10.1016/j.heares.2011.08.006
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发表时间：
2011-12
期刊：
影响因子：
2.8
通讯作者：
Shi X
中科院分区：
文献类型：
--
作者：
Shi X
正常的耳蜗血供对于建立耳蜗内电位和维持内淋巴的产生至关重要。长期以来，耳蜗微循环异常一直被认为是噪声性听力损失、老年性听力损失(老年性耳聋)、突发性听力损失或前庭功能障碍以及梅尼埃病的病因之一。了解耳蜗微循环的病理生理学机制具有重要的临床意义。更好地了解耳蜗血流量(CoBF)将有助于更有效地治疗由异常血流引起的听力障碍。这篇综述集中在耳蜗微血管的生理病理方面的最新发现和发现。
Normal blood supply to the cochlea is critically important for establishing the endocochlear potential and sustaining production of endolymph. Abnormal cochlear microcirculation has long been considered an etiologic factor in noise-induced hearing loss, age-related hearing loss (presbycusis), sudden hearing loss or vestibular function, and Meniere's disease. Knowledge of the mechanisms underlying the pathophysiology of cochlear microcirculation is of fundamental clinical importance. A better understanding of cochlear blood flow (CoBF) will enable more effective management of hearing disorders resulting from aberrant blood flow. This review focuses on recent discoveries and findings related to the physiopathology of the cochlear microvasculature.