STUDIES ON THE DYNAMICS OF TRANSMISSION OF ONCHOCERCIASIS IN A SUDAN-SAVANNA AREA OF NORTH CAMEROON .4. THE DIFFERENT EXPOSURE TO SIMULIUM BITES AND TRANSMISSION OF BOYS AND GIRLS AND MEN AND WOMEN, AND THE RESULTING MANIFESTATIONS OF ONCHOCERCIASIS
STUDIES ON THE DYNAMICS OF TRANSMISSION OF ONCHOCERCIASIS IN A SUDAN-SAVANNA AREA OF NORTH CAMEROON .4. THE DIFFERENT EXPOSURE TO SIMULIUM BITES AND TRANSMISSION OF BOYS AND GIRLS AND MEN AND WOMEN, AND THE RESULTING MANIFESTATIONS OF ONCHOCERCIASIS
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DOI：
10.1080/00034983.1987.11812118
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发表时间：
1987-06-01
影响因子：
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通讯作者：
ANDERSON, J
中科院分区：
文献类型：
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作者：
RENZ, A;FUGLSANG, H;ANDERSON, J
在喀麦隆苏丹稀树草原3个村庄附近的12个地点对人口停留时间进行了一年多的监测，一年前在那里测量了盘尾丝虫传播潜力。男孩在村庄外停留的时间更长，接触到的盘尾丝虫病传播的可能性是女孩的2.1至2.7倍，而男性的接触程度与女性相似或仅略高。男孩感染和眼部病变发病较早，臀部微丝蚴平均密度（2.2、9.4和79.3 mff snip1）明显高于女孩（分别为0.1、5.8和42.2 mff snip1）。这些差异在成年人群中保持不变，男性的平均微丝虫密度为52.3、80.4和183.1 mff snip1，女性为15.6、49.6和114.7 mff snip1。在这三个村庄中，盘尾丝虫病引起的眼部病变在男性人口中分别占5%、13%和55%，而在女性人口中分别占2%、3%和8%。接触疾病传播的程度与由此产生的皮肤微丝虫负荷之间存在密切关系，这在两性之间没有差异，盘尾丝虫病引起的眼部病变的发生也有类似的趋势。讨论了早期和重度感染对疾病表现演变的影响。
The sojourn time of the human population were monitored over one year at 12 sites in the vicinity of three villages in the Cameroon Sudan-savanna, where the Onchocerca volvulus transmission potentials has been measured one year previously. Boys stayed longer outside the villages, and were exposed 2.1 to 2.7 times more than girls to transmission of oncohocerciasis, whereas the exposure of men was similar or only moderately higher than the exposure of women. In boys, the onset of infections and ocular lesions was earlier and the average microfilarial density at the buttock (2.2, 9.4 and 79.3 mff snip-1) was much higher than in girls (0.1, 5.8 and 42.2 mff snip-1 at the three villages respectively). These differences were maintained in the adult population, where the average microfilarial density was 52.3, 80.4 and 183.1 mff snip-1 in men and 15.6, 49.6 and 114.7 mff snip-1 in women. Ocular lesions due to onchocerciasis were found in 5, 13 and 55% of the male population in the three villages, as compared with 2, 3 and 8% of the female population. There was a close relationship between the degree of exposure to the transmission of disease and the resulting microfilarial load in the skin which was not different for the two sexes, and a similar trend was seen for the occurrence of ocular lesions due to onchocerciasis. The influence of an early and heavy infection on the evolution of disease manifestations is discussed.