Synovial collagenase and joint diseases: the significancy of latent collagenase with special reference to rheumatoid arthritis.

Synovial collagenase and joint diseases: the significancy of latent collagenase with special reference to rheumatoid arthritis.
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滑膜胶原酶和关节疾病:潜在胶原酶的重要性,特别是类风湿性关节炎。

DOI:
10.1093/oxfordjournals.jbchem.a130154
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发表时间:
1973
影响因子:
2.7
通讯作者:
Y. Nagai
Y. Nagai
中科院分区:
生物学4区
文献类型:
--
作者:
S. Abe;M. Shinmei;Y. Nagai

文献摘要

被引文献

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材料与方法滑液:23例典型的和明确的类风湿性关节炎患者,16例骨关节炎患者,4例内部紊乱患者,4例单纯性滑膜炎(水肿)导致的水肿患者,2例痛风患者和1例系统性红斑狼疮患者来自立川共济医院和川崎市立医院骨科门诊和顺天堂胶原病门诊大学医院。根据美国风湿病协会的标准诊断风湿性关节炎。所有通过在2,000 μ g离心20 min去除细胞材料和纤维蛋白凝块的液体在-20 ℃下储存直至使用。
MATERIALS AND METHODSSynovial Fluids•\Synovial fluids from 23 patients with classical and definite rheumatoid arthritis, 16 with osteoarthritis, 4 with internal derangement, 4 with hydrops due to simple synovitis(hydrops), 2 with gout and 1 with systemic lupus erythematosus were obtained from the Orthopedic Outpatient Clinics of Tachikawa Kyosai Hospital and Kawasaki City Hospital and from the Collagen Disease Outpatient Clinic of Juntendo University Hospital. Rheumatoid arthritis was diagnosed according to the criteria of the American Rheumatism Association. All the fluids, freed of cellular materials and fibrin clots by centrifugation at 2,000•~ g for 20 min, were stored at-20• Ž until used.