Adolescent girls in Maine are at risk for vitamin D insufficiency
Adolescent girls in Maine are at risk for vitamin D insufficiency
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DOI：
10.1016/j.jada.2005.03.002
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发表时间：
2005-06-01
影响因子：
--
通讯作者：
Holick, MF
中科院分区：
文献类型：
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作者：
Sullivan, SS;Rosen, CJ;Holick, MF
目的是确定在一组健康的青少年生活在北方气候的血清25-羟维生素D（25-OHD）的季节性波动。2000年9月至2003年3月，23名9至11岁的女孩参加了这项研究。每年9月和3月测量血清25-OHD和甲状旁腺激素水平。每年夏季和冬季评估维生素D的膳食摄入量。夏季阳光照射的评估使用的户外活动时间的报告。从9月到3月，血清25-OHD平均下降28%。在23名受试者中的11名（48%）中观察到维生素D不足（至少一个血清25-OHD水平< 50 nmol/L）。23名受试者中有4名（17%）在9月和3月都表现出维生素D不足。从9月到3月，平均甲状旁腺激素水平增加了4皮克/毫升（15%）。在北方纬度地区，冬季需要增加维生素D的摄入量。
The objective was to determine the seasonal fluctuations in serum 25-hydroxyvitamin D (25-OHD) in a group of healthy adolescents living in a northern climate. Twenty-three 9- to 11-year-old girls participated in the study from September 2000 to March 2003. Serum 25-OHD and parathyroid hormone levels were measured each September and March. Dietary intake of vitamin D was assessed each summer and winter. Summer-sun exposure was evaluated using reports of time spent outdoors. The mean decrease in serum 25-OHD from September to March was 28%. Vitamin D insufficiency (at least one serum 25-OHD level < 50 nmol/L) was observed in 11 of 23 (48%) subjects. Four of 23 subjects (17%) exhibited vitamin D insufficiency in both September and March. Mean parathyroid hormone levels increased 4 pg/mL (15%) from September to March. Vitamin D intakes need to be increased in winter at northern latitudes.