Comparison of early versus late onset familial Mediterranean fever

Comparison of early versus late onset familial Mediterranean fever
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早发型与晚发型家族性地中海热的比较

DOI:
10.1111/1756-185x.13259
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发表时间:
2018
影响因子:
2.5
通讯作者:
T. Kaşifoğlu
T. Kaşifoğlu
中科院分区:
医学4区
文献类型:
--
作者:
N. Y. Yasar Bilge;I. Sari;D. Solmaz;S. Şenel;H. Emmungil;L. Kılıç;S. Yılmaz Oner;F. Yıldız;S. Yılmaz;D.E. Ersozlu Bozkirli;M. Aydın Tufan;S. Yılmaz;V. Yazısız;Y. Pehlivan;C. Beş;G. Yıldırım Çetin;Ş. Erten;E. Gonullu;F. Şahin;S. Akar;K. Aksu;U. Kalyoncu;H. Direskeneli;E. Erken;M. Sayarlıoğlu;M. Çınar;T. Kaşifoğlu

文献摘要

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家族性地中海热(FMF)是最常见的自身炎症性疾病。这种疾病的一个共同特点是它的年轻优势。近90%的患者在成年早期经历疾病发作。目前,有有限的数据比较早发性与迟发性FMF,因此,本研究的主要目的是调查这两个子集的某些人口统计学,临床和遗传差异。
Familial Mediterranean fever (FMF) is the most common autoinflammatory disease. One of the common characteristics of this disease is its young age predominance. Nearly 90% of patients experience disease flares during early adult age periods. Currently there are limited data for the comparison of early versus late onset FMF and therefore the primary aim of this study was to investigate these two subsets with regard to their certain demographic, clinical and genetic differences.