Incidence of Lower Urinary Tract Symptoms in a Population-based Study of Men and Women

Incidence of Lower Urinary Tract Symptoms in a Population-based Study of Men and Women
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DOI:
10.1016/j.urology.2013.05.009
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发表时间:
2013-09-01
期刊:
影响因子:
2.1
通讯作者:
McKinlay, John B.
McKinlay, John B.
中科院分区:
医学4区
文献类型:
--
作者:
Maserejian, Nancy N.;Chen, Shan;McKinlay, John B.

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目的报告下尿路症状(LUTS)在不同种族和年龄的美国的发病率。S.材料和方法我们进行了一项随访5年的前瞻性队列研究。采用分层2阶段整群随机抽样方法,招募5502名30-79岁的黑人、西班牙裔或白色人种或种族的波士顿居民。其中,4144人(1610名男性和2534名女性)完成了随访方案。美国泌尿外科协会症状指数被用来定义中度至重度LUTS.Results的3301名男性和女性没有或轻度LUTS在基线,5年的发病率中度至重度LUTS(美国泌尿外科协会症状指数>= 8)是11.4%的整体,女性高于男性(13.9%比8.5%,P = 0.02)。虽然发病率随年龄增长而增加(P <0.001),但在50-70岁的妇女中有一个平台期,然后在≥ 70岁的妇女中翻了一番,达到35.0%。白色男性有一个明显较低的发病率(7%)比所有其他性别和种族亚组(13%)。结论约1/10的成年人有新开发的LUTS在5年的后续在我们的研究中,与性别和种族或民族的差异,表明更大的发生泌尿系统问题的黑人和西班牙裔参与者和妇女。泌尿学82:560-564,2013年。(C)2013 Elsevier Inc.
OBJECTIVE To report the incidence of lower urinary tract symptoms (LUTS) in a racially and ethnically and age-diverse U. S. population-based sample of men and women.MATERIALS AND METHODS We conducted a prospective cohort study with 5 years of follow-up. A stratified 2-stage cluster random sampling method was used to recruit 5502 Boston residents aged 30-79 years of black, Hispanic, or white race or ethnicity. Of these, 4144 (1610 men and 2534 women) completed the follow-up protocol. The American Urological Association Symptom Index was used to define moderate-to-severe LUTS.RESULTS Of the 3301 men and women with no or mild LUTS at baseline, the 5-year incidence of moderate-to-severe LUTS (American Urological Association Symptom Index >= 8) was 11.4% overall and was higher for women than for men (13.9% vs 8.5%, P = .02). Although the incidence increased with age (P < .001), it had a plateau among women aged 50-70 years and then doubled to 35.0% among women aged >= 70 years. White men had a distinctly lower incidence (7%) than all other sex and race subgroups (13%).CONCLUSION Approximately 1 in 10 adults had newly developed LUTS at 5 years follow-up of in our study, with differences by sex and race or ethnicity, indicating a greater occurrence of urologic problems among black and Hispanic participants and women. UROLOGY 82: 560-564, 2013. (C) 2013 Elsevier Inc.